Primary lateral sclerosis
We’re all in this for good.
- help each other live better and uncover the best ways to manage your health today
- help researchers shorten the path to new treatments tomorrow
How much good can your data do? A whole lot, as co-founder Jamie Heywood explains in this video.
What is primary lateral sclerosis?
Primary lateral sclerosis (PLS) is a rare neuromuscular disease characterized by progressive muscle weakness in the voluntary muscles. PLS belongs to a group of disorders known as motor neuron diseases.
Common symptoms reported by people with primary lateral sclerosis
Treatments taken by people for primary lateral sclerosis

Let’s build this page together! When you share what it’s like to have primary lateral sclerosis through your profile, those stories and data appear here too.
Got a question about living with primary lateral sclerosis? Members in the forum might have the answers.
Compare treatments taken by people with primary lateral sclerosis

Let’s build this page together! When you share what it’s like to have primary lateral sclerosis through your profile, those stories and data appear here too.
Got a question about living with primary lateral sclerosis? Members in the forum might have the answers.
Who has primary lateral sclerosis on PatientsLikeMe?
- 0 new patients joined this month
- 831 say PLS is their primary condition
| Age | Proportion | # of patients |
|---|---|---|
| <20 | 0 | |
| 20s | 9 | |
| 30s | 67 | |
| 40s | 66 | |
| 50s | 65 | |
| 60s | 77 | |
| 70+ | 157 |
| Age at first symptom | Proportion | # of patients |
|---|---|---|
| 0-19 years | 45 | |
| 20-29 years | 34 | |
| 30-39 years | 44 | |
| 40-49 years | 31 | |
| 50-59 years | 29 | |
| 60-69 years | 23 | |
| 70+ years | 18 |
Distribution of sex
| Sex | Proportion | # of patients |
|---|---|---|
| Male | 307 | |
| Female | 452 |
| Diagnosis status | Proportion | # of patients |
|---|---|---|
| Diagnosed | 378 | |
| Not Diagnosed | 83 |