What is 5-Hydroxytryptophan (5-HTP)?

Category: Supplements

Most popular types: 5 HTP TR Natrol 5-HTP NOW 5-HTP Show all

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See also: 5-hydroxytryptophan and L-Theanine Endo Plus

5-Hydroxytryptophan or 5-HTP is a naturally-occurring amino acid marketed in the United States and other countries as a dietary supplement for use as an antidepressant, appetite suppressant, and sleep aid.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Depressed mood 66 35
Fibromyalgia 56 39
Insomnia 42 25
Major depressive disorder 15 16
Amyotrophic lateral sclerosis 14 6

Show all 75 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations Percentage
Severe 6
Moderate 9
Mild 17
None 100

Commonly reported side effects and conditions associated with 5-Hydroxytryptophan (5-HTP)

Side effect Patients Percentage
Nausea 3
Heart palpitations 2
Irritability 2
Vivid dreams 2
Agitation 1
Bipolar manic episodes 1

Show all 22 reported side effects

Why patients stopped taking 5-Hydroxytryptophan (5-HTP)

Multiple reasons could be selected

Reason Patients Percentage
Did not seem to work 37
Other 34
Expense 13
Side effects too severe 10
Doctor's advice 9
Course of treatment ended 8
Personal research 5
Change in health plan coverage 1
See all 96 patients who've stopped taking 5-Hydroxytryptophan (5-HTP)

Duration

Stopped taking 5-Hydroxytryptophan (5-HTP)

Duration Patients Percentage
Less than 1 month 19
1 - 6 months 37
6 months - 1 year 18
1 - 2 years 10
2 - 5 years 7
5 - 10 years 5
10 years or more 1
Adherence
Adherence Evaluations Percentage
Always 77
Usually 34
Sometimes 17
Never taken as prescribed 4
Burden
Burden Evaluations Percentage
Very hard to take 1
Somewhat hard to take 9
A little hard to take 20
Not at all hard to take 102
Cost per month
Cost per month Evaluations Percentage
$200+ 1
$100-199 0
$50-99 3
$25-49 19
< $25 73
Not specified 36
Last updated:

14 patient evaluations for 5-Hydroxytryptophan (5-HTP)

May 6, 2017 (Started Sep 15, 2016)

  • Effectiveness
    Major (for gastrointestinal dysmotility)
  • Side effects
    Mild (hot flash after eating, flushing)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 400 mg Daily
Advice & Tips: Pellentesque habitant morbi tristique senectus et netus et malesuada fames ac turpis egestas. Phasellus faucibus turpis sed mi maximus mattis.
Cost: < $25 monthly

  • 1 helpful mark

Dec 18, 2016 (Started Dec 08, 2012)

  • Effectiveness
    Moderate (for anxious mood)
  • Effectiveness
    Slight (for borderline personality disorder)
  • Effectiveness
    Slight (for depressed mood)
  • Effectiveness
    Moderate (for difficulty falling asleep)
  • Effectiveness
    Slight (for major depressive disorder)
  • Effectiveness
    Slight (for problems concentrating)
  • Effectiveness
    Slight (for sleep problems)
  • Side effects
    Moderate (vivid dreams)
  • Adherence
    Sometimes
  • Burden
    Not at all hard to take
Dosage: As needed
Advice & Tips: Pellentesque habitant morbi tristique senectus et netus et malesuada fames ac turpis egestas. Phasellus faucibus turpis sed mi maximus mattis.
Cost: < $25 monthly

Apr 2, 2016 (Started Dec 08, 2012)

  • Effectiveness
    Slight (for anxious mood)
  • Effectiveness
    Slight (for borderline personality disorder)
  • Effectiveness
    Moderate (for depressed mood)
  • Effectiveness
    Major (for difficulty falling asleep)
  • Effectiveness
    Moderate (for major depressive disorder)
  • Effectiveness
    Slight (for problems concentrating)
  • Effectiveness
    Moderate (for sleep problems)
  • Side effects
    Mild (vivid dreams)
  • Adherence
    Sometimes
  • Burden
    Not at all hard to take
Dosage: 100 mg Daily
Advice & Tips: Pellentesque habitant morbi tristique senectus et netus et malesuada fames ac turpis egestas. Phasellus faucibus turpis sed mi maximus mattis.
Cost: < $25 monthly

Aug 10, 2015 (Started Dec 08, 2012)

  • Effectiveness
    Slight (for anxious mood)
  • Effectiveness
    Slight (for borderline personality disorder)
  • Effectiveness
    Slight (for depressed mood)
  • Effectiveness
    Moderate (for difficulty falling asleep)
  • Side effects
    Mild (vivid dreams)
  • Adherence
    Sometimes
  • Burden
    Not at all hard to take
Dosage: As needed
Cost: < $25 monthly

Apr 1, 2014 (Started Dec 08, 2012)

  • Effectiveness
    Can't tell (for depressed mood)
  • Effectiveness
    Slight (for anxious mood)
  • Effectiveness
    Can't tell (for borderline personality disorder)
  • Side effects
    None
  • Adherence
    Usually
  • Burden
    Not at all hard to take
Dosage: 100 mg Daily
Advice & Tips: Pellentesque habitant morbi tristique senectus et netus et malesuada fames ac turpis egestas. Phasellus faucibus turpis sed mi maximus mattis.
Cost: < $25 monthly

Mar 8, 2013 (Started Dec 08, 2012)

  • Effectiveness
    Slight (for borderline personality disorder)
  • Effectiveness
    Slight (for anxious mood)
  • Effectiveness
    Slight (for depressed mood)
  • Side effects
    None
  • Adherence
    Sometimes
  • Burden
    Not at all hard to take
Dosage: As needed
Advice & Tips: Pellentesque habitant morbi tristique senectus et netus et malesuada fames ac turpis egestas. Phasellus faucibus turpis sed mi maximus mattis.
Cost: < $25 monthly

  • 0 helpful marks

Oct 5, 2016 (Started Jul 05, 2016)

  • Effectiveness
    Can't tell (for amyotrophic lateral sclerosis)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 200 mg Daily
Cost: < $25 monthly

  • 0 helpful marks
Last updated:
Showing 3 of 14 patient evaluations for 5-Hydroxytryptophan (5-HTP)