What is Alemtuzumab?
Category: Prescription Drugs
Most popular types: Lemtrada Campath
Alemtuzumab is commonly used as a single agent for the treatment of B-cell chronic lymphocytic leukemia (B-CLL) and multiple sclerosis.
| Purpose | Patients | Evaluations | Perceived Effectiveness |
|---|---|---|---|
| Multiple sclerosis | 583 | 101 | |
| Chronic lymphocytic leukemia | 18 | 0 | |
| T-cell prolymphocytic leukemia | 10 | 1 | |
| Participate in clinical trial | 4 | 2 | |
| Bone marrow transplant | 1 | 1 |
- Major
- Moderate
- Slight
- None
- Can't tell
Side effects
Side effects as an overall problem
| Severity | Evaluations | Percentage |
|---|---|---|
| Severe | 8 | |
| Moderate | 23 | |
| Mild | 36 | |
| None | 39 |
Commonly reported side effects and conditions associated with Alemtuzumab
| Side effect | Patients | Percentage |
|---|---|---|
| Headaches | 17 | |
| Fatigue | 16 | |
| Fever/chills | 7 | |
| Generalized weakness (asthenia) | 5 | |
| Hives (urticaria) | 5 | |
| Nausea | 4 |
Why patients stopped taking Alemtuzumab
Multiple reasons could be selected
| Reason | Patients | Percentage |
|---|---|---|
| Course of treatment ended | 15 | |
| Did not seem to work | 3 | |
| Other | 3 | |
| Doctor's advice | 1 |
Duration
Stopped taking Alemtuzumab
| Duration | Patients | Percentage |
|---|---|---|
| Less than 1 month | 17 | |
| 6 months - 1 year | 2 | |
| 1 - 2 years | 4 | |
| 2 - 5 years | 2 | |
| 5 - 10 years | 1 |
What people switch to and from
Patients started taking Alemtuzumab after stopping:
| Treatment | Patients | Percentage |
|---|---|---|
| Natalizumab (Tysabri) | 22 | |
| Dimethyl fumarate (Tecfidera) | 14 | |
| Fingolimod (Gilenya) | 7 | |
| Teriflunomide (Aubagio) | 6 | |
| Glatiramer acetate (Copaxone) | 5 |
Patients stopped taking Alemtuzumab and switched to:
| Treatment | Patients | Percentage |
|---|---|---|
| Ocrelizumab (Ocrevus) | 3 | |
| Dimethyl fumarate (Tecfidera) | 2 | |
| Fingolimod (Gilenya) | 1 | |
| Teriflunomide (Aubagio) | 1 |
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