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What is Amitriptyline?

Category: Prescription Drugs

Most popular types: Elavil Endep Trepiline Show all

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See also: Amantadine-amitriptyline-baclofen-clonidine-lidocaine-nifedipine-prilocaine Ketoprofen, Bupivacaine, Amitriptyline, Clonidine, Gabapentin , Ketamine, Cyclobenzaprine

Amitriptyline is a tricyclic antidepressant used for the treatment of depression. It may also be used for certain chronic and neuropathic (nerve) pain and for prevention of migraine headaches.

See patients taking Amitriptyline

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Insomnia 1217 755
Fibromyalgia 1097 644
Pain 1046 628
Peripheral neuropathy 742 93
Spinal cord injury 239 6

Show all 325 reasons taken

  • Major
  • Moderate
  • Slight
  • None
  • Can't tell
See all 13487 patients that have taken Amitriptyline

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations Percentage
Severe 294
Moderate 435
Mild 578
None 742

Commonly reported side effects and conditions associated with Amitriptyline

Side effect Patients Percentage
Dry mouth 186
Weight gain 132
Drowsiness 97
Sleepiness 64
Excessive daytime sleepiness (somnolence) 53
Grogginess 51

Show all 279 reported side effects

Why patients stopped taking Amitriptyline

Multiple reasons could be selected

Reason Patients Percentage
Did not seem to work 528
Side effects too severe 513
Doctor's advice 287
Other 192
Course of treatment ended 61
Personal research 59
Expense 18
Change in health plan coverage 13
See all 1239 patients who've stopped taking Amitriptyline

Duration

Stopped taking Amitriptyline

Duration Patients Percentage
Less than 1 month 221
1 - 6 months 321
6 months - 1 year 188
1 - 2 years 149
2 - 5 years 189
5 - 10 years 68
10 years or more 43
Adherence
Adherence Evaluations Percentage
Always 1630
Usually 253
Sometimes 76
Never taken as prescribed 90
Burden
Burden Evaluations Percentage
Very hard to take 96
Somewhat hard to take 128
A little hard to take 248
Not at all hard to take 1577
Cost per month
Cost per month Evaluations Percentage
$200+ 7
$100-199 3
$50-99 13
$25-49 29
< $25 1044
Not specified 953

What people switch to and from

Patients started taking Amitriptyline after stopping:

Treatment Patients Percentage
Duloxetine (Cymbalta) 24
Gabapentin (Neurontin) 16
Trazodone (Apo-Trazodone) 16
Pregabalin (Lyrica) 12
Topiramate (Topamax) 10

Show all 77 treatments patients report switching from

Patients stopped taking Amitriptyline and switched to:

Treatment Patients Percentage
Nortriptyline (Pamelor) 39
Gabapentin (Neurontin) 38
Duloxetine (Cymbalta) 30
Pregabalin (Lyrica) 26
Trazodone (Apo-Trazodone) 15

Show all 76 treatments patients report switching to

Last updated:

155 patient evaluations for Amitriptyline

Sort by: Most recent

Jan 20, 2021 (Started Oct 06, 2016)

  • Effectiveness
    Moderate (for insomnia)
  • Side effects
    Severe
  • Adherence
    Never taken as prescribed
  • Burden
    Very hard to take
Dosage: 10 mg Daily
Advice & Tips: Pellentesque habitant morbi tristique senectus et netus et malesuada fames ac turpis egestas. Phasellus faucibus turpis sed mi maximus mattis.
  • 0 helpful marks

Jan 11, 2021 (Started Apr 19, 2012)

  • Effectiveness
    Moderate (for major depressive disorder)
  • Effectiveness
    None (for increased need for sleep)
  • Side effects
    Mild (fluid retention weight gain, weight gain, slurred speech, hangover effect)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 200 mg Daily
Advice & Tips: Pellentesque habitant morbi tristique senectus et netus et malesuada fames ac turpis egestas. Phasellus faucibus turpis sed mi maximus mattis.

Dec 15, 2018 (Started Apr 19, 2012)

  • Effectiveness
    Slight (for increased need for sleep)
  • Effectiveness
    Moderate (for major depressive disorder)
  • Side effects
    Mild (fluid retention weight gain, weight gain, slurred speech, hangover effect)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 200 mg Daily
Advice & Tips: Pellentesque habitant morbi tristique senectus et netus et malesuada fames ac turpis egestas. Phasellus faucibus turpis sed mi maximus mattis.
Cost: < $25 monthly

Aug 13, 2018 (Started Apr 19, 2012)

  • Effectiveness
    Major (for increased need for sleep)
  • Effectiveness
    Major (for major depressive disorder)
  • Side effects
    Moderate (fluid retention weight gain, weight gain, slurred speech, hangover effect)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 200 mg Daily
Advice & Tips: Pellentesque habitant morbi tristique senectus et netus et malesuada fames ac turpis egestas. Phasellus faucibus turpis sed mi maximus mattis.
Cost: < $25 monthly

Dec 15, 2017 (Started Apr 19, 2012)

  • Effectiveness
    Major (for major depressive disorder)
  • Side effects
    Moderate (fluid retention weight gain, weight gain, slurred speech, hangover effect)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 200 mg Daily
Cost: < $25 monthly

Nov 10, 2017 (Started Apr 19, 2012)

  • Effectiveness
    Major (for major depressive disorder)
  • Side effects
    Mild (fluid retention weight gain, weight gain, slurred speech, hangover effect)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 200 mg Daily
Cost: < $25 monthly

Aug 2, 2016 (Started Apr 19, 2012)

  • Effectiveness
    Moderate (for major depressive disorder)
  • Side effects
    Mild (fluid retention weight gain, weight gain, slurred speech)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 200 mg Daily
Advice & Tips: Pellentesque habitant morbi tristique senectus et netus et malesuada fames ac turpis egestas. Phasellus faucibus turpis sed mi maximus mattis.
Cost: < $25 monthly
  • 0 helpful marks

Dec 17, 2020 (Started Jan 22, 2018)

  • Effectiveness
    Moderate (for insomnia)
  • Effectiveness
    Slight (for fibromyalgia)
  • Effectiveness
    Slight (for pain)
  • Effectiveness
    Slight (for undifferentiated connective tissue disease)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 30 mg Daily

Jan 27, 2018 (Started Jan 22, 2018)

  • Effectiveness
    Slight (for fibromyalgia)
  • Effectiveness
    Major (for insomnia)
  • Effectiveness
    Moderate (for pain)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 30 mg Daily
Cost: < $25 monthly
  • 0 helpful marks
Last updated:
Showing 3 of 155 patient evaluations for Amitriptyline