What is Bupropion?
Category: Prescription Drugs
Most popular types: Wellbutrin Wellbutrin XL Bupropion XL Show all
Bupropion is a type of antidepressant. It may be used to treat certain types of depression, such as major depressive disorder and seasonal affective disorder. It may also be used to help quit smoking and for the treatment of attention-deficit/hyperactivity and bipolar disorders.
| Purpose | Patients | Evaluations | Perceived Effectiveness |
|---|---|---|---|
| Major depressive disorder | 16214 | 1446 | |
| Depressed mood | 1905 | 861 | |
| Persistent depressive disorder (dysthymia) | 1256 | 344 | |
| Mild depression | 708 | 75 | |
| Tobacco use disorder | 167 | 45 | |
| Reactive depression | 152 | 18 |
- Major
- Moderate
- Slight
- None
- Can't tell
Side effects
Side effects as an overall problem
| Severity | Evaluations | Percentage |
|---|---|---|
| Severe | 304 | |
| Moderate | 406 | |
| Mild | 674 | |
| None | 1273 |
Commonly reported side effects and conditions associated with Bupropion
| Side effect | Patients | Percentage |
|---|---|---|
| Dry mouth | 116 | |
| Anxious mood | 75 | |
| Weight gain | 60 | |
| Insomnia | 56 | |
| Headaches | 50 | |
| Constipation | 46 |
Why patients stopped taking Bupropion
Multiple reasons could be selected
| Reason | Patients | Percentage |
|---|---|---|
| Did not seem to work | 778 | |
| Side effects too severe | 610 | |
| Doctor's advice | 467 | |
| Other | 309 | |
| Course of treatment ended | 103 | |
| Expense | 90 | |
| Personal research | 79 | |
| Change in health plan coverage | 47 |
Duration
Stopped taking Bupropion
| Duration | Patients | Percentage |
|---|---|---|
| Less than 1 month | 383 | |
| 1 - 6 months | 369 | |
| 6 months - 1 year | 244 | |
| 1 - 2 years | 235 | |
| 2 - 5 years | 301 | |
| 5 - 10 years | 143 | |
| 10 years or more | 76 |
What people switch to and from
Patients started taking Bupropion after stopping:
| Treatment | Patients | Percentage |
|---|---|---|
| Sertraline (Zoloft) | 114 | |
| Fluoxetine (Prozac) | 108 | |
| Venlafaxine (Effexor XR) | 90 | |
| Duloxetine (Cymbalta) | 64 | |
| Citalopram (Celexa) | 63 |
Patients stopped taking Bupropion and switched to:
| Treatment | Patients | Percentage |
|---|---|---|
| Duloxetine (Cymbalta) | 90 | |
| Venlafaxine (Effexor XR) | 81 | |
| Sertraline (Zoloft) | 76 | |
| Citalopram (Celexa) | 48 | |
| Escitalopram (Lexapro) | 48 |
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