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What is Carbidopa-Entacapone-Levodopa?

Category: Prescription Drugs

Most popular types: Stalevo Stalevo 100 Stalevo 150 Show all

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The combination of levodopa, carbidopa, and entacapone is used for Parkinson's Disease. Levodopa is the precursor to dopamine, carbidopa slows the breakdown of levodopa, while entacapone improves the efficacy of levodopa.

See patients taking Carbidopa-Entacapone-Levodopa

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Parkinson's disease 3260 309
Stiffness/spasticity 26 20
Increase effect of another treatment 15 14
Improve mobility 5 4
Tremor(s) 5 1

Show all 30 reasons taken

  • Major
  • Moderate
  • Slight
  • None
  • Can't tell
See all 3583 patients that have taken Carbidopa-Entacapone-Levodopa

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations Percentage
Severe 32
Moderate 73
Mild 80
None 139

Commonly reported side effects and conditions associated with Carbidopa-Entacapone-Levodopa

Side effect Patients Percentage
Jerky movements 37
Nausea 17
Cramps in legs 8
Dry mouth 8
Fatigue 7
Weight gain 6

Show all 90 reported side effects

Why patients stopped taking Carbidopa-Entacapone-Levodopa

Multiple reasons could be selected

Reason Patients Percentage
Side effects too severe 77
Doctor's advice 71
Did not seem to work 43
Other 41
Expense 21
Personal research 8
Change in health plan coverage 3
Course of treatment ended 1
See all 213 patients who've stopped taking Carbidopa-Entacapone-Levodopa

Duration

Stopped taking Carbidopa-Entacapone-Levodopa

Duration Patients Percentage
Less than 1 month 28
1 - 6 months 57
6 months - 1 year 36
1 - 2 years 22
2 - 5 years 48
5 - 10 years 14
10 years or more 6
Adherence
Adherence Evaluations Percentage
Always 240
Usually 64
Sometimes 7
Never taken as prescribed 13
Burden
Burden Evaluations Percentage
Very hard to take 17
Somewhat hard to take 33
A little hard to take 66
Not at all hard to take 208
Cost per month
Cost per month Evaluations Percentage
$200+ 19
$100-199 16
$50-99 30
$25-49 45
< $25 100
Not specified 114

What people switch to and from

Patients started taking Carbidopa-Entacapone-Levodopa after stopping:

Treatment Patients Percentage
Carbidopa-Levodopa (Sinemet) 39
Ropinirole (Requip) 8
Carbidopa Levodopa ER (Rytary XR) 3
Pramipexole (Mirapex) 3
Amantadine (Symmetrel) 2

Show all 12 treatments patients report switching from

Patients stopped taking Carbidopa-Entacapone-Levodopa and switched to:

Treatment Patients Percentage
Carbidopa-Levodopa (Sinemet) 21
Carbidopa Levodopa ER (Rytary XR) 16
Entacapone (Comtan) 5
Carbidopa-Levodopa CR (Sinemet CR) 3
Pramipexole (Mirapex) 3

Show all 12 treatments patients report switching to

Last updated:

42 patient evaluations for Carbidopa-Entacapone-Levodopa

Sort by: Most recent

Mar 26, 2018 (Started Jan 10, 2011)

  • Effectiveness
    Major (for Parkinson's disease)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 50-200-200 mg Three times daily
Advice & Tips: Pellentesque habitant morbi tristique senectus et netus et malesuada fames ac turpis egestas. Phasellus faucibus turpis sed mi maximus mattis.
Cost: < $25 monthly

Jun 8, 2016 (Started Jan 10, 2011)

  • Effectiveness
    Major (for Parkinson's disease)
  • Side effects
    None
  • Adherence
    Usually
  • Burden
    Not at all hard to take
Dosage: 50-200-200 mg Three times daily
Cost: < $25 monthly
  • 0 helpful marks

Jun 19, 2017 (Started Jul 01, 2011)

  • Effectiveness
    Slight (for Parkinson's disease)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 12.5-200-50 mg Three times daily
  • 0 helpful marks

Jun 13, 2017 (Started May 19, 2017)

  • Effectiveness
    None (for Parkinson's disease)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Advice & Tips: Pellentesque habitant morbi tristique senectus et netus et malesuada fames ac turpis egestas. Phasellus faucibus turpis sed mi maximus mattis.
Cost: $200+ monthly

Sep 16, 2015 (Started May 19, 2017)

  • Effectiveness
    Can't tell (for Parkinson's disease)
  • Effectiveness
    Can't tell (for stiffness/spasticity)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Advice & Tips: Pellentesque habitant morbi tristique senectus et netus et malesuada fames ac turpis egestas. Phasellus faucibus turpis sed mi maximus mattis.
Cost: $200+ monthly

Apr 13, 2015 (Started May 19, 2017)

  • Effectiveness
    Can't tell (for Parkinson's disease)
  • Effectiveness
    Can't tell (for stiffness/spasticity)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Advice & Tips: Pellentesque habitant morbi tristique senectus et netus et malesuada fames ac turpis egestas. Phasellus faucibus turpis sed mi maximus mattis.
Cost: $200+ monthly
  • 0 helpful marks
Last updated:
Showing 3 of 42 patient evaluations for Carbidopa-Entacapone-Levodopa