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What is Carbidopa-Levodopa?

Category: Prescription Drugs

Most popular types: Sinemet Carbidopa-Levodopa 25-100 Sinemet 25/100 Show all

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Levodopa is a dopamine precursor used to treat the movement disorder symptoms of Parkinson's disease. Carbidopa is often included with levodopa-containing drugs in order to boost its efficacy by slowing down the metabolism of dopamine.

See patients taking Carbidopa-Levodopa

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Parkinson's disease 14871 2162
Multiple system atrophy 304 64
Restless legs syndrome 165 73
Stiffness/spasticity 119 91
Dystonia 94 50
Progressive supranuclear palsy 90 15

Show all 105 reasons taken

  • Major
  • Moderate
  • Slight
  • None
  • Can't tell
See all 17378 patients that have taken Carbidopa-Levodopa

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations Percentage
Severe 101
Moderate 425
Mild 700
None 1078

Commonly reported side effects and conditions associated with Carbidopa-Levodopa

Side effect Patients Percentage
Jerky movements 166
Nausea 154
Drowsiness 48
Constipation 35
Headaches 28
Fatigue 22

Show all 293 reported side effects

Why patients stopped taking Carbidopa-Levodopa

Multiple reasons could be selected

Reason Patients Percentage
Doctor's advice 146
Did not seem to work 118
Side effects too severe 102
Other 84
Personal research 31
Course of treatment ended 19
Change in health plan coverage 9
Expense 5
See all 419 patients who've stopped taking Carbidopa-Levodopa

Duration

Stopped taking Carbidopa-Levodopa

Duration Patients Percentage
Less than 1 month 50
1 - 6 months 86
6 months - 1 year 54
1 - 2 years 67
2 - 5 years 98
5 - 10 years 43
10 years or more 19
Adherence
Adherence Evaluations Percentage
Always 1698
Usually 477
Sometimes 55
Never taken as prescribed 74
Burden
Burden Evaluations Percentage
Very hard to take 75
Somewhat hard to take 355
A little hard to take 575
Not at all hard to take 1299
Cost per month
Cost per month Evaluations Percentage
$200+ 29
$100-199 28
$50-99 69
$25-49 194
< $25 1252
Not specified 732

What people switch to and from

Patients started taking Carbidopa-Levodopa after stopping:

Treatment Patients Percentage
Ropinirole (Requip) 58
Pramipexole (Mirapex) 48
Rasagiline (Azilect) 29
Amantadine (Symmetrel) 27
Carbidopa-Entacapone-Levodopa (Stalevo) 21

Show all 21 treatments patients report switching from

Patients stopped taking Carbidopa-Levodopa and switched to:

Treatment Patients Percentage
Carbidopa Levodopa ER (Rytary XR) 92
Carbidopa-Entacapone-Levodopa (Stalevo) 39
Ropinirole (Requip) 20
Pramipexole (Mirapex) 17
Amantadine (Symmetrel) 14

Show all 23 treatments patients report switching to

Last updated:

133 patient evaluations for Carbidopa-Levodopa

Sort by: Most recent

Jan 22, 2021 (Started Jun 30, 2004)

  • Effectiveness
    Major (for Parkinson's disease)
  • Effectiveness
    Moderate (for restless legs syndrome)
  • Side effects
    Moderate (headache, headaches, tardive dyskinesia)
  • Adherence
    Always
  • Burden
    Somewhat hard to take
Dosage: 1 tablet(s) Four times daily

Jun 26, 2020 (Started Jun 30, 2004)

  • Effectiveness
    Major (for Parkinson's disease)
  • Effectiveness
    Moderate (for restless legs syndrome)
  • Side effects
    Moderate (headache, headaches, tardive dyskinesia)
  • Adherence
    Usually
  • Burden
    Somewhat hard to take
Dosage: 1 tablet(s) Four times daily
Cost: < $25 monthly

Mar 1, 2020 (Started Jun 30, 2004)

  • Effectiveness
    Major (for Parkinson's disease)
  • Effectiveness
    Major (for restless legs syndrome)
  • Side effects
    Moderate (headache, headaches, tardive dyskinesia)
  • Adherence
    Usually
  • Burden
    A little hard to take
Dosage: 0.5 tablet(s) Daily
Advice & Tips: Pellentesque habitant morbi tristique senectus et netus et malesuada fames ac turpis egestas. Phasellus faucibus turpis sed mi maximus mattis.
Cost: < $25 monthly

Jan 12, 2017 (Started Jun 30, 2004)

  • Effectiveness
    Major (for Parkinson's disease)
  • Effectiveness
    Major (for restless legs syndrome)
  • Side effects
    Mild (headache, headaches, tardive dyskinesia)
  • Adherence
    Always
  • Burden
    A little hard to take
Dosage: 25 mg-100 mg Three times daily
Advice & Tips: Pellentesque habitant morbi tristique senectus et netus et malesuada fames ac turpis egestas. Phasellus faucibus turpis sed mi maximus mattis.
Cost: < $25 monthly

Apr 24, 2016 (Started Jun 30, 2004)

  • Effectiveness
    Moderate (for Parkinson's disease)
  • Effectiveness
    Can't tell (for restless legs syndrome)
  • Side effects
    Mild (headache, headaches, tardive dyskinesia)
  • Adherence
    Usually
  • Burden
    Somewhat hard to take
Dosage: 25 mg-100 mg Three times daily
Advice & Tips: Pellentesque habitant morbi tristique senectus et netus et malesuada fames ac turpis egestas. Phasellus faucibus turpis sed mi maximus mattis.
Cost: < $25 monthly

Nov 26, 2015 (Started Jun 30, 2004)

  • Effectiveness
    Moderate (for Parkinson's disease)
  • Effectiveness
    Moderate (for restless legs syndrome)
  • Side effects
    Mild (headache, headaches)
  • Adherence
    Usually
  • Burden
    Very hard to take
Dosage: 25 mg-100 mg Three times daily
Advice & Tips: Pellentesque habitant morbi tristique senectus et netus et malesuada fames ac turpis egestas. Phasellus faucibus turpis sed mi maximus mattis.
Cost: < $25 monthly

Jun 5, 2015 (Started Jun 30, 2004)

  • Effectiveness
    Major (for Parkinson's disease)
  • Effectiveness
    Can't tell (for restless legs syndrome)
  • Side effects
    Mild (headache, headaches)
  • Adherence
    Usually
  • Burden
    Somewhat hard to take
Dosage: 25 mg-100 mg Three times daily
Advice & Tips: Pellentesque habitant morbi tristique senectus et netus et malesuada fames ac turpis egestas. Phasellus faucibus turpis sed mi maximus mattis.
Cost: < $25 monthly

Feb 11, 2015 (Started Jun 30, 2004)

  • Effectiveness
    Major (for restless legs syndrome)
  • Effectiveness
    Moderate (for Parkinson's disease)
  • Side effects
    None
  • Adherence
    Usually
  • Burden
    Somewhat hard to take
Dosage: 25 mg-100 mg Three times daily
Advice & Tips: Pellentesque habitant morbi tristique senectus et netus et malesuada fames ac turpis egestas. Phasellus faucibus turpis sed mi maximus mattis.
Cost: < $25 monthly

Nov 10, 2014 (Started Jun 30, 2004)

  • Effectiveness
    Moderate (for Parkinson's disease)
  • Side effects
    None
  • Adherence
    Usually
  • Burden
    A little hard to take
Dosage: 25 mg-100 mg Three times daily
Advice & Tips: Pellentesque habitant morbi tristique senectus et netus et malesuada fames ac turpis egestas. Phasellus faucibus turpis sed mi maximus mattis.
Cost: < $25 monthly
  • 1 helpful mark

Jan 2, 2021 (Started Aug 18, 2011)

  • Effectiveness
    Slight (for Parkinson's disease)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 3 x 25 mg-100 mg Daily

Oct 17, 2020 (Started Aug 18, 2011)

  • Effectiveness
    Slight (for Parkinson's disease)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 3 x 25 mg-100 mg Daily
Cost: < $25 monthly

Oct 28, 2018 (Started Aug 18, 2011)

  • Effectiveness
    Can't tell (for Parkinson's disease)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 3 x 25 mg-100 mg Daily
Cost: < $25 monthly

Jul 15, 2018 (Started Aug 18, 2011)

  • Effectiveness
    Slight (for Parkinson's disease)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 3 x 25 mg-100 mg Daily
Cost: < $25 monthly

Mar 22, 2017 (Started Aug 18, 2011)

  • Effectiveness
    Moderate (for Parkinson's disease)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 3 x 25 mg-100 mg Daily
Cost: < $25 monthly

Dec 9, 2016 (Started Aug 18, 2011)

  • Effectiveness
    Slight (for Parkinson's disease)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 3 x 25 mg-100 mg Daily
Cost: < $25 monthly

Jun 16, 2016 (Started Aug 18, 2011)

  • Effectiveness
    Slight (for Parkinson's disease)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 3 x 25 mg-100 mg Daily
Cost: < $25 monthly

Dec 22, 2015 (Started Aug 18, 2011)

  • Effectiveness
    Slight (for Parkinson's disease)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 3 x 25 mg-100 mg Daily
Cost: < $25 monthly

Nov 21, 2013 (Started Aug 18, 2011)

  • Effectiveness
    Slight (for Parkinson's disease)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 3 x 25 mg-100 mg Daily
Cost: < $25 monthly

Dec 6, 2012 (Started Aug 18, 2011)

  • Effectiveness
    Slight (for Parkinson's disease)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 3 x 25 mg-100 mg Daily
Cost: < $25 monthly

Sep 5, 2011 (Started Aug 18, 2011)

  • Effectiveness
    Slight (for Parkinson's disease)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 3 x 25 mg-100 mg Daily
Cost: < $25 monthly
  • 0 helpful marks

Apr 27, 2020 (Started Aug 02, 2013)

  • Effectiveness
    Major (for Parkinson's disease)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Cost: < $25 monthly

Aug 15, 2018 (Started Aug 02, 2013)

  • Effectiveness
    Major (for Parkinson's disease)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 3 x 25-100 mg Five times daily
Advice & Tips: Pellentesque habitant morbi tristique senectus et netus et malesuada fames ac turpis egestas. Phasellus faucibus turpis sed mi maximus mattis.
Cost: < $25 monthly

Nov 4, 2015 (Started Aug 02, 2013)

  • Effectiveness
    Major (for Parkinson's disease)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 1 tablet(s) Four times daily

May 31, 2015 (Started Aug 02, 2013)

  • Effectiveness
    Major (for Parkinson's disease)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 1 tablet(s) Four times daily
  • 1 helpful mark
Last updated:
Showing 3 of 133 patient evaluations for Carbidopa-Levodopa