What is Carbidopa-Levodopa CR?

Category: Prescription Drugs

Most popular types: Sinemet CR Carbilev Half Sinemet CR Show all

false

A controlled release preparation of carbidopa/levodopa formulated to release a lower, smoother dose of medication. It is sometimes taken last thing at night in order to maintain dopamine levels throughout sleep and into the morning.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Parkinson's disease 331 170
Stiffness/spasticity 40 17
Improve mobility 15 10
Slow movement (bradykinesia) 6 1
Tremor in hands 6 3

Show all 42 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations Percentage
Severe 12
Moderate 31
Mild 38
None 123

Commonly reported side effects and conditions associated with Carbidopa-Levodopa CR

Side effect Patients Percentage
Jerky movements 13
Vivid dreams 10
Fatigue 8
Nausea 7
Amber colored urine 4
Back pain 4

Show all 41 reported side effects

Why patients stopped taking Carbidopa-Levodopa CR

Multiple reasons could be selected

Reason Patients Percentage
Doctor's advice 39
Did not seem to work 24
Other 20
Side effects too severe 13
Personal research 5
Course of treatment ended 3
Change in health plan coverage 1
Expense 1
See all 88 patients who've stopped taking Carbidopa-Levodopa CR

Duration

Stopped taking Carbidopa-Levodopa CR

Duration Patients Percentage
Less than 1 month 11
1 - 6 months 20
6 months - 1 year 7
1 - 2 years 17
2 - 5 years 17
5 - 10 years 12
10 years or more 5
Adherence
Adherence Evaluations Percentage
Always 147
Usually 41
Sometimes 6
Never taken as prescribed 10
Burden
Burden Evaluations Percentage
Very hard to take 8
Somewhat hard to take 16
A little hard to take 59
Not at all hard to take 121
Cost per month
Cost per month Evaluations Percentage
$200+ 4
$100-199 4
$50-99 6
$25-49 6
< $25 107
Not specified 77

What people switch to and from

Patients started taking Carbidopa-Levodopa CR after stopping:

Treatment Patients Percentage
Carbidopa-Levodopa (Sinemet) 13
Carbidopa-Entacapone-Levodopa (Stalevo) 3
Carbidopa Levodopa ER (Rytary XR) 3
Amantadine (Symmetrel) 1
Apomorphine (Apokyn) 1

Show all 9 treatments patients report switching from

Patients stopped taking Carbidopa-Levodopa CR and switched to:

Treatment Patients Percentage
Carbidopa-Levodopa (Sinemet) 10
Carbidopa Levodopa ER (Rytary XR) 5
Carbidopa-Entacapone-Levodopa (Stalevo) 2
Acetaminophen (Paracetamol) (Tylenol) 1
Apomorphine (Apokyn) 1

Show all 7 treatments patients report switching to

Last updated:

32 patient evaluations for Carbidopa-Levodopa CR

Apr 11, 2018 (Started Jan 01, 2006)

  • Effectiveness
    Moderate (for Parkinson's disease)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 50 mg-200 mg Daily
Advice & Tips: Pellentesque habitant morbi tristique senectus et netus et malesuada fames ac turpis egestas. Phasellus faucibus turpis sed mi maximus mattis.
Cost: < $25 monthly

Nov 4, 2017 (Started Jan 01, 2006)

  • Effectiveness
    Moderate (for Parkinson's disease)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 50 mg-200 mg Daily
Cost: < $25 monthly

Aug 10, 2017 (Started Jan 01, 2006)

  • Effectiveness
    Moderate (for Parkinson's disease)
  • Side effects
    Moderate (breakthrough pain)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 50 mg-200 mg Daily
Cost: < $25 monthly

May 25, 2017 (Started Jan 01, 2006)

  • Effectiveness
    Major (for Parkinson's disease)
  • Side effects
    Moderate (breakthrough pain)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 50 mg-200 mg Daily
Advice & Tips: Pellentesque habitant morbi tristique senectus et netus et malesuada fames ac turpis egestas. Phasellus faucibus turpis sed mi maximus mattis.
Cost: < $25 monthly

Jan 17, 2017 (Started Jan 01, 2006)

  • Effectiveness
    Major (for Parkinson's disease)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 50 mg-200 mg Daily
Advice & Tips: Pellentesque habitant morbi tristique senectus et netus et malesuada fames ac turpis egestas. Phasellus faucibus turpis sed mi maximus mattis.
Cost: < $25 monthly

Oct 10, 2016 (Started Jan 01, 2006)

  • Effectiveness
    Major (for Parkinson's disease)
  • Side effects
    Mild (breakthrough pain)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 50 mg-200 mg Daily
Advice & Tips: Pellentesque habitant morbi tristique senectus et netus et malesuada fames ac turpis egestas. Phasellus faucibus turpis sed mi maximus mattis.
Cost: < $25 monthly

Sep 14, 2016 (Started Jan 01, 2006)

  • Effectiveness
    Moderate (for Parkinson's disease)
  • Side effects
    Mild (breakthrough pain)
  • Adherence
    Always
  • Burden
    A little hard to take
Dosage: 50 mg-200 mg Daily
Advice & Tips: Pellentesque habitant morbi tristique senectus et netus et malesuada fames ac turpis egestas. Phasellus faucibus turpis sed mi maximus mattis.
Cost: < $25 monthly

Jul 13, 2016 (Started Jan 01, 2006)

  • Effectiveness
    Major (for Parkinson's disease)
  • Side effects
    Mild (breakthrough pain)
  • Adherence
    Always
  • Burden
    A little hard to take
Dosage: 50 mg-200 mg Daily
Advice & Tips: Pellentesque habitant morbi tristique senectus et netus et malesuada fames ac turpis egestas. Phasellus faucibus turpis sed mi maximus mattis.
Cost: < $25 monthly

Nov 18, 2015 (Started Jan 01, 2006)

  • Effectiveness
    Moderate (for Parkinson's disease)
  • Side effects
    Mild (breakthrough pain)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 50 mg-200 mg Daily
Advice & Tips: Pellentesque habitant morbi tristique senectus et netus et malesuada fames ac turpis egestas. Phasellus faucibus turpis sed mi maximus mattis.
Cost: < $25 monthly

Sep 16, 2015 (Started Jan 01, 2006)

  • Effectiveness
    Major (for Parkinson's disease)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 50 mg-200 mg Daily
Cost: < $25 monthly

Jul 15, 2015 (Started Jan 01, 2006)

  • Effectiveness
    Moderate (for Parkinson's disease)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 50 mg-200 mg Daily
Cost: < $25 monthly

  • 0 helpful marks

Aug 2, 2017 (Started May 15, 2017)

  • Effectiveness
    Moderate (for muscle spasms at night)
  • Effectiveness
    Moderate (for Parkinson's disease)
  • Side effects
    Mild (weight gain, exhausting dreams)
  • Adherence
    Always
  • Burden
    A little hard to take
Dosage: 200 mg Daily
Advice & Tips: Pellentesque habitant morbi tristique senectus et netus et malesuada fames ac turpis egestas. Phasellus faucibus turpis sed mi maximus mattis.
Cost: < $25 monthly

May 6, 2009 (Started May 15, 2017)

  • Effectiveness
    Slight (for Parkinson's disease)
  • Effectiveness
    Slight (for muscle spasms at night)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take

  • 0 helpful marks

Jun 26, 2017 (Started Jul 17, 2011)

  • Effectiveness
    Major (for Parkinson's disease)
  • Side effects
    None
  • Adherence
    Usually
  • Burden
    Not at all hard to take
Advice & Tips: Pellentesque habitant morbi tristique senectus et netus et malesuada fames ac turpis egestas. Phasellus faucibus turpis sed mi maximus mattis.
Cost: < $25 monthly

Mar 15, 2017 (Started Jul 17, 2011)

  • Effectiveness
    Major (for Parkinson's disease)
  • Side effects
    None
  • Adherence
    Never taken as prescribed
  • Burden
    Not at all hard to take
Dosage: 50 mg-200 mg Daily
Cost: < $25 monthly

  • 0 helpful marks
Last updated:
Showing 3 of 32 patient evaluations for Carbidopa-Levodopa CR