What is Cyclosporine?
Category: Prescription Drugs
Most popular types: Neoral Gengraf Sandimmune
Cyclosporin is an immunosuppressant drug widely used in post-allogeneic organ transplant to reduce the activity of the patient's immune system and so the risk of organ rejection. It has been studied in transplants of skin, heart, kidney, lung, pancreas, bone marrow and small intestine.
| Purpose | Patients | Evaluations | Perceived Effectiveness |
|---|---|---|---|
| Prevent organ rejection | 346 | 36 | |
| Psoriasis | 142 | 7 | |
| Psoriatic arthritis | 82 | 6 | |
| Crohn's disease | 34 | 2 | |
| Aplastic anemia | 30 | 1 |
- Major
- Moderate
- Slight
- None
- Can't tell
Side effects
Side effects as an overall problem
| Severity | Evaluations | Percentage |
|---|---|---|
| Severe | 11 | |
| Moderate | 34 | |
| Mild | 17 | |
| None | 16 |
Commonly reported side effects and conditions associated with Cyclosporine
| Side effect | Patients | Percentage |
|---|---|---|
| Hair growth | 9 | |
| Nausea | 4 | |
| Muscle and joint pain | 3 | |
| Constipation | 2 | |
| Elevated blood pressure | 2 | |
| Fatigue | 2 |
Why patients stopped taking Cyclosporine
Multiple reasons could be selected
| Reason | Patients | Percentage |
|---|---|---|
| Doctor's advice | 53 | |
| Side effects too severe | 35 | |
| Did not seem to work | 22 | |
| Other | 21 | |
| Course of treatment ended | 10 | |
| Personal research | 4 | |
| Change in health plan coverage | 2 | |
| Expense | 1 |
Duration
Stopped taking Cyclosporine
| Duration | Patients | Percentage |
|---|---|---|
| Less than 1 month | 17 | |
| 1 - 6 months | 11 | |
| 6 months - 1 year | 17 | |
| 1 - 2 years | 11 | |
| 2 - 5 years | 17 | |
| 5 - 10 years | 12 | |
| 10 years or more | 12 |
What people switch to and from
Patients started taking Cyclosporine after stopping:
| Treatment | Patients | Percentage |
|---|---|---|
| Methotrexate (Apo-Methotrexate) | 4 | |
| Acitretin (Soriatane) | 1 | |
| Adalimumab (Humira) | 1 | |
| Azathioprine (Imuran) | 1 | |
| Betamethasone topical (Betnovate) | 1 |
Patients stopped taking Cyclosporine and switched to:
| Treatment | Patients | Percentage |
|---|---|---|
| Azathioprine (Imuran) | 2 | |
| Methotrexate (Apo-Methotrexate) | 2 | |
| Adalimumab (Humira) | 1 | |
| Anakinra (Kineret) | 1 | |
| Leflunomide (Arava) | 1 |
Last updated: