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What is Dalfampridine?

Category: Prescription Drugs

Most popular types: Ampyra Fampyra

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Dalfampridine is an extended release formulation of 4-aminopyridine or 4-AP. It is a potassium channel blocker that is used as a treatment to improve walking in patients with multiple sclerosis (MS). Dalfampridine was previously called Fampridine-SR during clinical trials.

See patients taking Dalfampridine

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Multiple sclerosis 2059 714
Walking problems 1919 579
Improve mobility 318 331
Fatigue 34 30
Improve flexibility/strength 34 38
Balance problems 29 36

Show all 48 reasons taken

  • Major
  • Moderate
  • Slight
  • None
  • Can't tell
See all 4492 patients that have taken Dalfampridine

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations Percentage
Severe 57
Moderate 69
Mild 183
None 662

Commonly reported side effects and conditions associated with Dalfampridine

Side effect Patients Percentage
Insomnia 29
Dizziness 22
Nausea 17
Headaches 12
Constipation 11
Balance problems 10

Show all 106 reported side effects

Why patients stopped taking Dalfampridine

Multiple reasons could be selected

Reason Patients Percentage
Did not seem to work 219
Side effects too severe 115
Other 71
Expense 56
Doctor's advice 52
Change in health plan coverage 19
Course of treatment ended 12
Personal research 9
See all 401 patients who've stopped taking Dalfampridine

Duration

Stopped taking Dalfampridine

Duration Patients Percentage
Less than 1 month 87
1 - 6 months 113
6 months - 1 year 46
1 - 2 years 60
2 - 5 years 54
5 - 10 years 16
10 years or more 7
Adherence
Adherence Evaluations Percentage
Always 793
Usually 114
Sometimes 23
Never taken as prescribed 41
Burden
Burden Evaluations Percentage
Very hard to take 15
Somewhat hard to take 41
A little hard to take 105
Not at all hard to take 810
Cost per month
Cost per month Evaluations Percentage
$200+ 53
$100-199 57
$50-99 94
$25-49 247
< $25 259
Not specified 261

What people switch to and from

Patients started taking Dalfampridine after stopping:

Treatment Patients Percentage
Glatiramer acetate (Copaxone) 7
Fampridine (4-AP immediate release) 4
Dimethyl fumarate (Tecfidera) 2
Natalizumab (Tysabri) 2
Baclofen (Mylan-Baclofen) 1

Show all 9 treatments patients report switching from

Patients stopped taking Dalfampridine and switched to:

Treatment Patients Percentage
Teriflunomide (Aubagio) 3
Dimethyl fumarate (Tecfidera) 2
Natalizumab (Tysabri) 2
Amifampridine phosphate (3,4 Diaminopyridine) 1
Cyclophosphamide (Cytoxan) 1

Show all 11 treatments patients report switching to

Last updated:

78 patient evaluations for Dalfampridine

Sort by: Most recent

Nov 30, 2020 (Started Jul 01, 2007)

  • Effectiveness
    Moderate (for multiple sclerosis)
  • Effectiveness
    Moderate (for walking problems)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 10 mg Twice daily
Advice & Tips: Pellentesque habitant morbi tristique senectus et netus et malesuada fames ac turpis egestas. Phasellus faucibus turpis sed mi maximus mattis.

Jan 23, 2020 (Started Jul 01, 2007)

  • Effectiveness
    None (for multiple sclerosis)
  • Effectiveness
    Moderate (for walking problems)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 10 mg Twice daily
Advice & Tips: Pellentesque habitant morbi tristique senectus et netus et malesuada fames ac turpis egestas. Phasellus faucibus turpis sed mi maximus mattis.
  • 0 helpful marks

Oct 9, 2017 (Started Apr 21, 2014)

  • Effectiveness
    Can't tell (for multiple sclerosis)
  • Side effects
    None
  • Adherence
    Never taken as prescribed
  • Burden
    Not at all hard to take
Dosage: 20 mg Daily
Advice & Tips: Pellentesque habitant morbi tristique senectus et netus et malesuada fames ac turpis egestas. Phasellus faucibus turpis sed mi maximus mattis.
Cost: < $25 monthly
  • 0 helpful marks

Jun 24, 2017 (Started Apr 15, 2012)

  • Effectiveness
    Can't tell (for walking problems)
  • Effectiveness
    None (for multiple sclerosis)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 2 tablet(s) Daily
Advice & Tips: Pellentesque habitant morbi tristique senectus et netus et malesuada fames ac turpis egestas. Phasellus faucibus turpis sed mi maximus mattis.
Cost: $100-199 monthly

Mar 28, 2017 (Started Apr 15, 2012)

  • Effectiveness
    Can't tell (for multiple sclerosis)
  • Effectiveness
    Can't tell (for walking problems)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 2 tablet(s) Daily
Advice & Tips: Pellentesque habitant morbi tristique senectus et netus et malesuada fames ac turpis egestas. Phasellus faucibus turpis sed mi maximus mattis.
Cost: < $25 monthly

Feb 26, 2015 (Started Apr 15, 2012)

  • Effectiveness
    Moderate (for multiple sclerosis)
  • Side effects
    None
  • Adherence
    Usually
  • Burden
    Not at all hard to take
Dosage: 2 tablet(s) Daily
Advice & Tips: Pellentesque habitant morbi tristique senectus et netus et malesuada fames ac turpis egestas. Phasellus faucibus turpis sed mi maximus mattis.
Cost: < $25 monthly

Jun 26, 2013 (Started Apr 15, 2012)

  • Effectiveness
    Major (for multiple sclerosis)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 2 tablet(s) Daily
Advice & Tips: Pellentesque habitant morbi tristique senectus et netus et malesuada fames ac turpis egestas. Phasellus faucibus turpis sed mi maximus mattis.
Cost: $100-199 monthly
  • 0 helpful marks
Last updated:
Showing 3 of 78 patient evaluations for Dalfampridine