What is Desvenlafaxine?
Category: Prescription Drugs
Most popular types: Pristiq Exsira
Desvenlafaxine is a serotonin-norepinephrine reuptake inhibitor (SNRI). It is an extended release formulation believed to treat depression by affecting the levels of serotonin and norepinephrine, two neurotransmitters associated with depression.
| Purpose | Patients | Evaluations | Perceived Effectiveness |
|---|---|---|---|
| Depressed mood | 299 | 178 | |
| Major depressive disorder | 273 | 165 | |
| Anxious mood | 128 | 96 | |
| Fibromyalgia | 42 | 34 | |
| Bipolar disorder | 25 | 13 | |
| Pain | 14 | 9 |
- Major
- Moderate
- Slight
- None
- Can't tell
Side effects
Side effects as an overall problem
| Severity | Evaluations | Percentage |
|---|---|---|
| Severe | 57 | |
| Moderate | 70 | |
| Mild | 92 | |
| None | 177 |
Commonly reported side effects and conditions associated with Desvenlafaxine
| Side effect | Patients | Percentage |
|---|---|---|
| Decreased sex drive (libido) | 15 | |
| Weight gain | 12 | |
| Nausea | 11 | |
| Dizziness | 9 | |
| Dry mouth | 8 | |
| Decreased appetite | 7 |
Why patients stopped taking Desvenlafaxine
Multiple reasons could be selected
| Reason | Patients | Percentage |
|---|---|---|
| Did not seem to work | 97 | |
| Side effects too severe | 68 | |
| Doctor's advice | 48 | |
| Expense | 42 | |
| Other | 33 | |
| Change in health plan coverage | 12 | |
| Personal research | 7 | |
| Course of treatment ended | 6 |
Duration
Stopped taking Desvenlafaxine
| Duration | Patients | Percentage |
|---|---|---|
| Less than 1 month | 34 | |
| 1 - 6 months | 67 | |
| 6 months - 1 year | 45 | |
| 1 - 2 years | 38 | |
| 2 - 5 years | 27 | |
| 5 - 10 years | 8 | |
| 10 years or more | 1 |
What people switch to and from
Patients started taking Desvenlafaxine after stopping:
| Treatment | Patients | Percentage |
|---|---|---|
| Venlafaxine (Effexor XR) | 30 | |
| Duloxetine (Cymbalta) | 22 | |
| Fluoxetine (Prozac) | 21 | |
| Escitalopram (Lexapro) | 17 | |
| Bupropion (Wellbutrin) | 14 |
Patients stopped taking Desvenlafaxine and switched to:
| Treatment | Patients | Percentage |
|---|---|---|
| Duloxetine (Cymbalta) | 13 | |
| Venlafaxine (Effexor XR) | 12 | |
| Fluoxetine (Prozac) | 8 | |
| Vortioxetine (Trintellix) | 8 | |
| Escitalopram (Lexapro) | 5 |
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