What is Dextromethorphan-Quinidine?
Category: Prescription Drugs
Most popular types: Nuedexta 07-AVR-123 OLE
A dextromethorphan-quinidine combination was studied for its effect on inappropriate laughing and crying episodes experienced by some patients with brain injury or brain degeneration due to certain diseases. The incongruous laughing and crying episodes are due to pseudobulbar affect.
| Purpose | Patients | Evaluations | Perceived Effectiveness |
|---|---|---|---|
| Emotional lability | 124 | 115 | |
| Amyotrophic lateral sclerosis | 108 | 87 | |
| Doctor recommendation | 24 | 25 | |
| Pseudobulbar affect | 18 | 12 | |
| Swallowing difficulty (dysphagia) | 7 | 7 |
- Major
- Moderate
- Slight
- None
- Can't tell
Side effects
Side effects as an overall problem
| Severity | Evaluations | Percentage |
|---|---|---|
| Severe | 9 | |
| Moderate | 17 | |
| Mild | 20 | |
| None | 148 |
Commonly reported side effects and conditions associated with Dextromethorphan-Quinidine
| Side effect | Patients | Percentage |
|---|---|---|
| Diarrhea | 5 | |
| Dizziness | 4 | |
| Nausea | 4 | |
| Sleepiness | 4 | |
| Dry mouth | 3 | |
| Balance problems | 2 |
Why patients stopped taking Dextromethorphan-Quinidine
Multiple reasons could be selected
| Reason | Patients | Percentage |
|---|---|---|
| Did not seem to work | 12 | |
| Side effects too severe | 10 | |
| Other | 4 | |
| Expense | 3 | |
| Course of treatment ended | 2 | |
| Doctor's advice | 2 |
Duration
Stopped taking Dextromethorphan-Quinidine
| Duration | Patients | Percentage |
|---|---|---|
| Less than 1 month | 10 | |
| 1 - 6 months | 9 | |
| 6 months - 1 year | 5 | |
| 1 - 2 years | 2 | |
| 2 - 5 years | 3 | |
| 5 - 10 years | 2 |
What people switch to and from
Patients started taking Dextromethorphan-Quinidine after stopping:
| Treatment | Patients | Percentage |
|---|---|---|
| Venlafaxine (Effexor XR) | 2 | |
| Amitriptyline (Elavil) | 1 | |
| Sertraline (Zoloft) | 1 |
Patients stopped taking Dextromethorphan-Quinidine and switched to:
| Treatment | Patients | Percentage |
|---|---|---|
| Sertraline (Zoloft) | 2 | |
| Alprazolam (Xanax) | 1 | |
| Aripiprazole (Abilify) | 1 | |
| Glycopyrrolate (Robinul) | 1 | |
| Liothyronine (T3) (Cytomel) | 1 |
Last updated: