What is Estradiol?
Category: Prescription Drugs
Most popular types: Estrace Vivelle-Dot Patch Climara HRT patch Show all
See also: Bi-Est Dienogest-Estradiol Estradiol-norethindrone Estrogen patch Maxim Natazia
Estradiol, an estrogen derivative is used to treat menopausal symptoms, vaginal atrophy, hypoestrogenism; palliation of prostate and breast cancer; prevention of osteoporosis; abnormal uterine bleeding; and postmenopausal urinary symptoms (urgency, dysuria).
| Purpose | Patients | Evaluations | Perceived Effectiveness |
|---|---|---|---|
| Hormone replacement | 54 | 24 | |
| General health | 35 | 13 | |
| Hot flashes | 26 | 7 | |
| Gender dysphoria | 11 | 13 | |
| Support hormone balance | 11 | 2 |
- Major
- Moderate
- Slight
- None
- Can't tell
Side effects
Side effects as an overall problem
| Severity | Evaluations | Percentage |
|---|---|---|
| Severe | 6 | |
| Moderate | 14 | |
| Mild | 27 | |
| None | 101 |
Commonly reported side effects and conditions associated with Estradiol
| Side effect | Patients | Percentage |
|---|---|---|
| Hot flashes | 3 | |
| Breast tenderness | 2 | |
| Fatigue | 2 | |
| Headaches | 2 | |
| Migraine headaches | 2 | |
| Nausea | 2 |
Why patients stopped taking Estradiol
Multiple reasons could be selected
| Reason | Patients | Percentage |
|---|---|---|
| Doctor's advice | 25 | |
| Other | 20 | |
| Did not seem to work | 11 | |
| Course of treatment ended | 7 | |
| Expense | 7 | |
| Personal research | 6 | |
| Side effects too severe | 5 | |
| Change in health plan coverage | 4 |
Duration
Stopped taking Estradiol
| Duration | Patients | Percentage |
|---|---|---|
| Less than 1 month | 2 | |
| 1 - 6 months | 14 | |
| 6 months - 1 year | 9 | |
| 1 - 2 years | 15 | |
| 2 - 5 years | 19 | |
| 5 - 10 years | 10 | |
| 10 years or more | 8 |
What people switch to and from
Patients started taking Estradiol after stopping:
| Treatment | Patients | Percentage |
|---|---|---|
| Estrogen derivative (Premarin) | 13 | |
| Estradiol (Estrace) | 4 | |
| Estradiol Patch (Estrogen patch) | 4 | |
| Bioidentical hormones (Bi-Est) | 2 | |
| Ethinyl estradiol-norethindrone (Lo Loestrin FE) | 2 |
Patients stopped taking Estradiol and switched to:
| Treatment | Patients | Percentage |
|---|---|---|
| Estradiol (Estrace) | 4 | |
| Estradiol Patch (Estrogen patch) | 4 | |
| Estrogen derivative (Premarin) | 3 | |
| Amlodipine-olmesartan (Azor) | 1 | |
| Bioidentical hormones (Bi-Est) | 1 |
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