What is Everolimus?
Category: Prescription Drugs
Most popular types: Afinitor Zortress Certican
Everolimus is an antineoplastic agent used in the treatment of advanced renal cell cancer, after not having therapeutic response with sunitinib or sorafenib. It is also used as an immunosuppressant following solid organ transplant.
| Purpose | Patients | Evaluations | Perceived Effectiveness |
|---|---|---|---|
| Neuroendocrine tumor | 7 | 8 | |
| Breast cancer | 3 | 2 | |
| Pancreatic neuroendocrine tumor | 3 | 0 | |
| Kidney transplant | 2 | 1 | |
| Angiomyolipomatosis | 1 | 1 |
- Major
- Moderate
- Slight
- None
- Can't tell
Side effects
Side effects as an overall problem
| Severity | Evaluations | Percentage |
|---|---|---|
| Severe | 5 | |
| Moderate | 3 | |
| Mild | 7 | |
| None | 4 |
Commonly reported side effects and conditions associated with Everolimus
| Side effect | Patients | Percentage |
|---|---|---|
| Mouth sores (ulcers) | 4 | |
| Decreased appetite | 2 | |
| Dry skin | 2 | |
| Fatigue | 2 | |
| Hair loss | 2 | |
| Decreased sex drive (libido) | 1 |
Duration
Stopped taking Everolimus
| Duration | Patients | Percentage |
|---|---|---|
| 1 - 6 months | 4 | |
| 6 months - 1 year | 2 | |
| 1 - 2 years | 1 |
What people switch to and from
Patients started taking Everolimus after stopping:
| Treatment | Patients | Percentage |
|---|---|---|
| Capecitabine (Xeloda) | 1 | |
| Letrozole (Femara) | 1 | |
| Nivolumab (Opdivo) | 1 | |
| Octreotide (Sandostatin) | 1 | |
| Palbociclib (Ibrance) | 1 |
Patients stopped taking Everolimus and switched to:
| Treatment | Patients | Percentage |
|---|---|---|
| Capecitabine (Xeloda) | 1 | |
| Palbociclib (Ibrance) | 1 | |
| Temozolomide (Temodar) | 1 |
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