What is Fampridine (4-AP immediate release)?

Category: Prescription Drugs

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Fampridine, also known as by its chemical name 4-aminopyridine or 4-AP, a potassium channel blocker that is used to improve walking in patients with Multiple Sclerosis. Fampridine is an immediate release formulation of 4-AP that is compounded by pharmacist.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Improve mobility 28 22
Weakness in leg(s) 10 13
Multiple sclerosis 7 7
Walking problems 5 3
Balance problems 3 8
Stiffness/spasticity 3 1

Show all 14 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations Percentage
Severe 0
Moderate 5
Mild 15
None 20

Commonly reported side effects and conditions associated with Fampridine (4-AP immediate release)

Side effect Patients Percentage
Headaches 2
Balance problems 1
Bladder pain 1
Bowel irregularity 1
Chills 1
Head tingling 1

Show all 14 reported side effects

Why patients stopped taking Fampridine (4-AP immediate release)

Multiple reasons could be selected

Reason Patients Percentage
Did not seem to work 8
Other 7
Course of treatment ended 3
Side effects too severe 2
Personal research 1
See all 20 patients who've stopped taking Fampridine (4-AP immediate release)

Duration

Stopped taking Fampridine (4-AP immediate release)

Duration Patients Percentage
Less than 1 month 2
1 - 6 months 6
6 months - 1 year 2
1 - 2 years 4
2 - 5 years 3
10 years or more 1
Adherence
Adherence Evaluations Percentage
Always 32
Usually 4
Sometimes 2
Never taken as prescribed 2
Burden
Burden Evaluations Percentage
Very hard to take 0
Somewhat hard to take 3
A little hard to take 8
Not at all hard to take 29
Cost per month
Cost per month Evaluations Percentage
$200+ 6
$100-199 1
$50-99 11
$25-49 10
< $25 5
Not specified 7

What people switch to and from

Patients started taking Fampridine (4-AP immediate release) after stopping:

Treatment Patients Percentage
Dalfampridine (Ampyra) 1

Patients stopped taking Fampridine (4-AP immediate release) and switched to:

Treatment Patients Percentage
Dalfampridine (Ampyra) 4
Last updated:

1 patient evaluation for Fampridine (4-AP immediate release)

Feb 5, 2011 (Started Aug 01, 2007)

  • Effectiveness
    Major (for Other)
  • Side effects
    Mild (irritation in back of throat)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 20 mg Daily
Advice & Tips: Pellentesque habitant morbi tristique senectus et netus et malesuada fames ac turpis egestas. Phasellus faucibus turpis sed mi maximus mattis.
Cost: < $25 monthly
Side effects: irritation in back of throat

Jun 25, 2010 (Started Aug 01, 2007)

  • Effectiveness
    Slight (for Other)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    A little hard to take
Dosage: 20 mg Daily
Advice & Tips: Pellentesque habitant morbi tristique senectus et netus et malesuada fames ac turpis egestas. Phasellus faucibus turpis sed mi maximus mattis.
Side effects: irritation in back of throat

Jan 12, 2009 (Started Aug 01, 2007)

  • Effectiveness
    None (for Other)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    A little hard to take
Dosage: 20 mg Daily
Advice & Tips: Pellentesque habitant morbi tristique senectus et netus et malesuada fames ac turpis egestas. Phasellus faucibus turpis sed mi maximus mattis.
Side effects: irritation in back of throat

  • 0 helpful marks
Last updated:
Showing 1 of 1 patient evaluation for Fampridine (4-AP immediate release)