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What is 5-methyltetrahydrofolate (5-MTHF)?

Category: Supplements

Most popular types: FolaPro

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5-MTHF is an acronym for 5-methyltetrahydrofolate, also known as L-5-methyltetrahydrofolate (L-5-MTHF). It is the metabolically active form of folic acid that plays a role in DNA synthesis and repair.

See patients taking 5-methyltetrahydrofolate (5-MTHF)

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Methylenetetrahydrofolate reductase deficiency 12 5
Folic acid deficiency 6 5
Fibromyalgia 2 2
Major depressive disorder 2 2
Amyotrophic lateral sclerosis 1 0
Autoimmune disease undefined 1 1

Show all 12 reasons taken

  • Major
  • Moderate
  • Slight
  • None
  • Can't tell
See all 54 patients that have taken 5-methyltetrahydrofolate (5-MTHF)

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations Percentage
Severe 0
Moderate 0
Mild 1
None 13

Commonly reported side effects and conditions associated with 5-methyltetrahydrofolate (5-MTHF)

Side effect Patients Percentage
Flushing 1
Heart palpitations 1
Nausea 1

Why patients stopped taking 5-methyltetrahydrofolate (5-MTHF)

Multiple reasons could be selected

Reason Patients Percentage
Did not seem to work 4
Expense 4
Course of treatment ended 2
Other 2
Doctor's advice 1
See all 9 patients who've stopped taking 5-methyltetrahydrofolate (5-MTHF)

Duration

Stopped taking 5-methyltetrahydrofolate (5-MTHF)

Duration Patients Percentage
Less than 1 month 1
1 - 6 months 3
6 months - 1 year 1
1 - 2 years 1
2 - 5 years 3
Adherence
Adherence Evaluations Percentage
Always 11
Usually 3
Sometimes 0
Never taken as prescribed 0
Burden
Burden Evaluations Percentage
Very hard to take 0
Somewhat hard to take 0
A little hard to take 2
Not at all hard to take 12
Cost per month
Cost per month Evaluations Percentage
$200+ 0
$100-199 1
$50-99 3
$25-49 2
< $25 4
Not specified 4
Last updated:

1 patient evaluation for 5-methyltetrahydrofolate (5-MTHF)

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May 9, 2019 (Started Apr 15, 2019)

  • Effectiveness
    Major (for fibromyalgia)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 750 mcg Daily
Advice & Tips: Pellentesque habitant morbi tristique senectus et netus et malesuada fames ac turpis egestas. Phasellus faucibus turpis sed mi maximus mattis.
Cost: < $25 monthly

Aug 14, 2012 (Started Apr 15, 2019)

  • Effectiveness
    Major (for Methylation)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Advice & Tips: Pellentesque habitant morbi tristique senectus et netus et malesuada fames ac turpis egestas. Phasellus faucibus turpis sed mi maximus mattis.
Cost: < $25 monthly
  • 0 helpful marks
Last updated:
Showing 1 of 1 patient evaluation for 5-methyltetrahydrofolate (5-MTHF)