What is Fluoxetine?
Category: Prescription Drugs
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Fluoxetine is a selective serotonin reuptake inhibitor (SSRI) antidepressant. It is used to treat major depressive disorder, moderate to severe bulimia nervosa, obsessive compulsive and panic disorders. It may also be used for selective mutism and dementia related agitation.
| Purpose | Patients | Evaluations | Perceived Effectiveness |
|---|---|---|---|
| Major depressive disorder | 14459 | 902 | |
| Depressed mood | 5864 | 872 | |
| Post-traumatic stress disorder | 5106 | 239 | |
| Persistent depressive disorder (dysthymia) | 1022 | 164 | |
| Mild depression | 772 | 119 | |
| Borderline personality disorder | 729 | 72 |
- Major
- Moderate
- Slight
- None
- Can't tell
Side effects
Side effects as an overall problem
| Severity | Evaluations | Percentage |
|---|---|---|
| Severe | 213 | |
| Moderate | 371 | |
| Mild | 525 | |
| None | 906 |
Commonly reported side effects and conditions associated with Fluoxetine
| Side effect | Patients | Percentage |
|---|---|---|
| Decreased sex drive (libido) | 77 | |
| Sexual dysfunction | 73 | |
| Nausea | 70 | |
| Weight gain | 69 | |
| Anxious mood | 44 | |
| Fatigue | 37 |
Why patients stopped taking Fluoxetine
Multiple reasons could be selected
| Reason | Patients | Percentage |
|---|---|---|
| Did not seem to work | 909 | |
| Side effects too severe | 511 | |
| Doctor's advice | 488 | |
| Other | 314 | |
| Personal research | 105 | |
| Course of treatment ended | 97 | |
| Expense | 45 | |
| Change in health plan coverage | 42 |
Duration
Stopped taking Fluoxetine
| Duration | Patients | Percentage |
|---|---|---|
| Less than 1 month | 293 | |
| 1 - 6 months | 311 | |
| 6 months - 1 year | 280 | |
| 1 - 2 years | 272 | |
| 2 - 5 years | 304 | |
| 5 - 10 years | 162 | |
| 10 years or more | 147 |
What people switch to and from
Patients started taking Fluoxetine after stopping:
| Treatment | Patients | Percentage |
|---|---|---|
| Sertraline (Zoloft) | 94 | |
| Venlafaxine (Effexor XR) | 73 | |
| Citalopram (Celexa) | 66 | |
| Duloxetine (Cymbalta) | 55 | |
| Escitalopram (Lexapro) | 45 |
Patients stopped taking Fluoxetine and switched to:
| Treatment | Patients | Percentage |
|---|---|---|
| Duloxetine (Cymbalta) | 161 | |
| Venlafaxine (Effexor XR) | 152 | |
| Sertraline (Zoloft) | 143 | |
| Bupropion (Wellbutrin) | 108 | |
| Escitalopram (Lexapro) | 75 |
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