What is Lactulose?
Category: Prescription Drugs
Most popular types: Generlac Duphalac Kristalose Show all
Lactulose is a laxative drug taken as an oral syrup and used to treat constipation. It is also used in the prevention and treatment of portal-systemic encephalopathy, a neuropsychiatric syndrome associated with liver disease.
| Purpose | Patients | Evaluations | Perceived Effectiveness |
|---|---|---|---|
| Irritable bowel syndrome | 253 | 16 | |
| Constipation | 101 | 52 | |
| Bowel problems | 25 | 14 | |
| Chronic constipation | 6 | 5 | |
| High ammonia levels | 5 | 2 |
- Major
- Moderate
- Slight
- None
- Can't tell
Side effects
Side effects as an overall problem
| Severity | Evaluations | Percentage |
|---|---|---|
| Severe | 10 | |
| Moderate | 14 | |
| Mild | 10 | |
| None | 51 |
Commonly reported side effects and conditions associated with Lactulose
| Side effect | Patients | Percentage |
|---|---|---|
| Diarrhea | 7 | |
| Abdominal cramps | 3 | |
| Abdominal bloating | 2 | |
| Excessive gas | 2 | |
| Nausea | 2 | |
| Bowel incontinence | 1 |
Why patients stopped taking Lactulose
Multiple reasons could be selected
| Reason | Patients | Percentage |
|---|---|---|
| Did not seem to work | 26 | |
| Other | 19 | |
| Doctor's advice | 18 | |
| Side effects too severe | 14 | |
| Course of treatment ended | 9 | |
| Change in health plan coverage | 3 | |
| Personal research | 3 | |
| Expense | 2 |
Duration
Stopped taking Lactulose
| Duration | Patients | Percentage |
|---|---|---|
| Less than 1 month | 15 | |
| 1 - 6 months | 14 | |
| 6 months - 1 year | 12 | |
| 1 - 2 years | 11 | |
| 2 - 5 years | 6 | |
| 5 - 10 years | 8 | |
| 10 years or more | 2 |
What people switch to and from
Patients started taking Lactulose after stopping:
| Treatment | Patients | Percentage |
|---|---|---|
| Lubiprostone (Amitiza) | 1 | |
| Naloxegol (Movantik) | 1 |
Patients stopped taking Lactulose and switched to:
| Treatment | Patients | Percentage |
|---|---|---|
| Polyethylene glycol 3350 with electrolytes (GoLYTELY) | 3 | |
| Lubiprostone (Amitiza) | 2 | |
| Polyethylene Glycol 3350 (MiraLax) | 2 | |
| Rifaximin (Xifaxan) | 2 | |
| Bisacodyl (Dulcolax) | 1 |
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