What is Leucovorin?

Category: Prescription Drugs

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See also: CALGB 9251

Leucovorin is a vitamin derivative. This medication is used to prevent or treat the toxicities of medications known as folic acid antagonists including methotrexate, trimethoprim, pyrimethamine.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Treat side effects of another treatment 27 12
Rheumatoid arthritis 12 4
Osteosarcoma 6 0
Granulomatosis with polyangiitis (Wegener's) 5 0
Colon cancer 4 0
Amyotrophic lateral sclerosis 2 0

Show all 18 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations Percentage
Severe 0
Moderate 1
Mild 1
None 15

Commonly reported side effects and conditions associated with Leucovorin

Side effect Patients Percentage

Why patients stopped taking Leucovorin

Multiple reasons could be selected

Reason Patients Percentage
Course of treatment ended 4
Did not seem to work 3
Doctor's advice 2
Expense 1
Other 1
Personal research 1
Side effects too severe 1
See all 14 patients who've stopped taking Leucovorin

Duration

Stopped taking Leucovorin

Duration Patients Percentage
Less than 1 month 4
1 - 6 months 2
6 months - 1 year 3
1 - 2 years 1
2 - 5 years 1
5 - 10 years 3
Adherence
Adherence Evaluations Percentage
Always 13
Usually 3
Sometimes 0
Never taken as prescribed 1
Burden
Burden Evaluations Percentage
Very hard to take 0
Somewhat hard to take 0
A little hard to take 1
Not at all hard to take 16
Cost per month
Cost per month Evaluations Percentage
$200+ 0
$100-199 0
$50-99 0
$25-49 0
< $25 5
Not specified 12

What people switch to and from

Patients started taking Leucovorin after stopping:

Treatment Patients Percentage
Chemotherapy 1
Folic Acid (Folic Acid Prescription) 1

Patients stopped taking Leucovorin and switched to:

Treatment Patients Percentage
Apremilast (Otezla) 1
Last updated:
There are no evaluations for Leucovorin.