What is Linaclotide?
Category: Prescription Drugs
Most popular types: Linzess Constella
Linaclotide is a medication used to control abdominal pain in patients with irritable bowel syndrome.
| Purpose | Patients | Evaluations | Perceived Effectiveness |
|---|---|---|---|
| Constipation | 83 | 30 | |
| Irritable bowel syndrome | 59 | 26 | |
| Bowel problems | 21 | 7 | |
| Chronic constipation | 8 | 3 | |
| Bowel irritability | 6 | 1 | |
| Abdominal bloating | 1 | 1 |
- Major
- Moderate
- Slight
- None
- Can't tell
Side effects
Side effects as an overall problem
| Severity | Evaluations | Percentage |
|---|---|---|
| Severe | 9 | |
| Moderate | 9 | |
| Mild | 16 | |
| None | 18 |
Commonly reported side effects and conditions associated with Linaclotide
| Side effect | Patients | Percentage |
|---|---|---|
| Diarrhea | 13 | |
| Abdominal bloating | 6 | |
| Excessive gas | 3 | |
| Abdominal cramps | 2 | |
| Bowel irritability | 2 | |
| Morning diarrhea | 2 |
Duration
Stopped taking Linaclotide
| Duration | Patients | Percentage |
|---|---|---|
| Less than 1 month | 9 | |
| 1 - 6 months | 8 | |
| 6 months - 1 year | 5 | |
| 1 - 2 years | 4 | |
| 2 - 5 years | 2 | |
| 5 - 10 years | 1 |
What people switch to and from
Patients started taking Linaclotide after stopping:
| Treatment | Patients | Percentage |
|---|---|---|
| Lubiprostone (Amitiza) | 5 | |
| Polyethylene Glycol 3350 (MiraLax) | 3 | |
| Amitriptyline (Elavil) | 1 | |
| Dicyclomine (Bentyl) | 1 | |
| Docusate (Stool Softener) | 1 |
Patients stopped taking Linaclotide and switched to:
| Treatment | Patients | Percentage |
|---|---|---|
| Lubiprostone (Amitiza) | 7 | |
| Dicyclomine (Bentyl) | 2 | |
| Plecanatide (Trulance) | 1 | |
| Polyethylene Glycol 3350 (MiraLax) | 1 | |
| prucalopride (Motegrity) | 1 |
Last updated: