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What is Lubiprostone?

Category: Prescription Drugs

Most popular types: Amitiza

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Lubiprostone is a gastrointestinal agent used for the treatment of chronic idiopathic constipation; treatment of irritable bowel syndrome with constipation in adult women.

See patients taking Lubiprostone

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Constipation 109 64
Bowel problems 33 20
Bowel irritability 32 19
Irritable bowel syndrome 19 8
Chronic constipation 8 1
Bowel obstruction 2 1

Show all 18 reasons taken

  • Major
  • Moderate
  • Slight
  • None
  • Can't tell
See all 442 patients that have taken Lubiprostone

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations Percentage
Severe 3
Moderate 12
Mild 29
None 46

Commonly reported side effects and conditions associated with Lubiprostone

Side effect Patients Percentage
Diarrhea 8
Nausea 5
Abdominal bloating 3
Abdominal pain 2
Chronic diarrhea 2
Loose bowel movements 2

Show all 16 reported side effects

Why patients stopped taking Lubiprostone

Multiple reasons could be selected

Reason Patients Percentage
Other 17
Did not seem to work 15
Side effects too severe 12
Expense 10
Doctor's advice 9
Change in health plan coverage 3
Course of treatment ended 2
Personal research 1
See all 47 patients who've stopped taking Lubiprostone

Duration

Stopped taking Lubiprostone

Duration Patients Percentage
Less than 1 month 12
1 - 6 months 10
6 months - 1 year 6
1 - 2 years 11
2 - 5 years 3
5 - 10 years 3
10 years or more 1
Adherence
Adherence Evaluations Percentage
Always 60
Usually 13
Sometimes 13
Never taken as prescribed 4
Burden
Burden Evaluations Percentage
Very hard to take 1
Somewhat hard to take 6
A little hard to take 17
Not at all hard to take 66
Cost per month
Cost per month Evaluations Percentage
$200+ 1
$100-199 2
$50-99 8
$25-49 16
< $25 29
Not specified 34

What people switch to and from

Patients started taking Lubiprostone after stopping:

Treatment Patients Percentage
Linaclotide (Linzess) 7
Polyethylene Glycol 3350 (MiraLax) 3
Lactulose (Generlac) 2
Dicyclomine (Bentyl) 1
Hydrocortisone suppositories (Anucort HC) 1

Show all 9 treatments patients report switching from

Patients stopped taking Lubiprostone and switched to:

Treatment Patients Percentage
Linaclotide (Linzess) 5
Polyethylene Glycol 3350 (MiraLax) 2
Amitriptyline (Elavil) 1
Lactulose (Generlac) 1
Naloxegol (Movantik) 1

Show all 6 treatments patients report switching to

Last updated:

5 patient evaluations for Lubiprostone

Sort by: Most recent

May 15, 2020 (Started Aug 28, 2019)

  • Effectiveness
    Major (for constipation)
  • Side effects
    None
  • Adherence
    Usually
  • Burden
    Not at all hard to take
Dosage: 24 mcg Twice daily
  • 0 helpful marks

Mar 8, 2017 (Started Nov 08, 2011)

  • Effectiveness
    Slight (for bowel irritability)
  • Effectiveness
    Moderate (for bowel problems)
  • Effectiveness
    Slight (for constipation)
  • Side effects
    None
  • Adherence
    Sometimes
  • Burden
    A little hard to take
Dosage: 48 mcg Daily
Cost: < $25 monthly
  • 0 helpful marks

Dec 10, 2013 (Started Mar 15, 2013)

  • Effectiveness
    Moderate (for irritable bowel syndrome)
  • Effectiveness
    Slight (for constipation)
  • Effectiveness
    Moderate (for bowel irritability)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 16 mcg Daily
Advice & Tips: Pellentesque habitant morbi tristique senectus et netus et malesuada fames ac turpis egestas. Phasellus faucibus turpis sed mi maximus mattis.
Cost: $50-99 monthly
  • 0 helpful marks
Last updated:
Showing 3 of 5 patient evaluations for Lubiprostone