What is Melatonin?

Category: Supplements

Most popular types: NatureMade Melatonin Circadin Natrol Melatonin Show all

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See also: Angelicalm Spray

Melatonin appears to be the primary sleep-regulating hormone of the body. It has been used by individuals suffering from insomnia, particularly when adjusting to shift-work cycles or jet lag. In the US Melatonin is available over-the-counter, however, it may require a prescription in some countries.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Insomnia 603 252
Difficulty staying asleep 300 118
Periodic limb movement disorder 35 5
Unrefreshing or poor sleep 26 14
General health 24 8

Show all 89 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations Percentage
Severe 16
Moderate 33
Mild 67
None 426

Commonly reported side effects and conditions associated with Melatonin

Side effect Patients Percentage
Drowsiness 14
Vivid dreams 7
Depressed mood 6
Grogginess in morning 5
Excessive daytime sleepiness (somnolence) 4
Fatigue 4

Show all 57 reported side effects

Why patients stopped taking Melatonin

Multiple reasons could be selected

Reason Patients Percentage
Did not seem to work 135
Other 87
Doctor's advice 44
Side effects too severe 33
Course of treatment ended 19
Personal research 17
Expense 16
See all 302 patients who've stopped taking Melatonin

Duration

Stopped taking Melatonin

Duration Patients Percentage
Less than 1 month 49
1 - 6 months 80
6 months - 1 year 50
1 - 2 years 45
2 - 5 years 41
5 - 10 years 24
10 years or more 12
Adherence
Adherence Evaluations Percentage
Always 331
Usually 109
Sometimes 82
Never taken as prescribed 20
Burden
Burden Evaluations Percentage
Very hard to take 5
Somewhat hard to take 17
A little hard to take 66
Not at all hard to take 454
Cost per month
Cost per month Evaluations Percentage
$200+ 0
$100-199 0
$50-99 1
$25-49 18
< $25 224
Not specified 299

What people switch to and from

Patients started taking Melatonin after stopping:

Treatment Patients Percentage
Trazodone (Apo-Trazodone) 3
Clonazepam (Klonopin) 1
Hydroxyzine (Vistaril) 1
Lorazepam (Ativan) 1
Quetiapine (Seroquel) 1

Show all 6 treatments patients report switching from

Patients stopped taking Melatonin and switched to:

Treatment Patients Percentage
Trazodone (Apo-Trazodone) 2
Bupropion (Wellbutrin) 1
Clonazepam (Klonopin) 1
Clonidine (Catapres) 1
Diazepam (Valium) 1

Show all 8 treatments patients report switching to

Last updated:

46 patient evaluations for Melatonin

Jan 22, 2021 (Started Jul 15, 2017)

  • Effectiveness
    Slight (for REM sleep behavior disorder)
  • Side effects
    None
  • Adherence
    Usually
  • Burden
    A little hard to take
Dosage: 10 mg Daily

Mar 1, 2020 (Started Jul 15, 2017)

  • Effectiveness
    Slight (for REM sleep behavior disorder)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 10 mg Daily
Advice & Tips: Pellentesque habitant morbi tristique senectus et netus et malesuada fames ac turpis egestas. Phasellus faucibus turpis sed mi maximus mattis.
Cost: < $25 monthly

Sep 20, 2017 (Started Jul 15, 2017)

  • Effectiveness
    Slight (for REM sleep behavior disorder)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 5 mg Daily
Advice & Tips: Pellentesque habitant morbi tristique senectus et netus et malesuada fames ac turpis egestas. Phasellus faucibus turpis sed mi maximus mattis.

Aug 18, 2017 (Started Jul 15, 2017)

  • Effectiveness
    Slight (for REM sleep behavior disorder)
  • Side effects
    None
  • Adherence
    Usually
  • Burden
    Not at all hard to take
Dosage: 5 mg Daily
Advice & Tips: Pellentesque habitant morbi tristique senectus et netus et malesuada fames ac turpis egestas. Phasellus faucibus turpis sed mi maximus mattis.

  • 0 helpful marks

Jun 25, 2020 (Started Nov 15, 2011)

  • Effectiveness
    Major (for abnormal dreams)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 10 mg Daily
Advice & Tips: Pellentesque habitant morbi tristique senectus et netus et malesuada fames ac turpis egestas. Phasellus faucibus turpis sed mi maximus mattis.
Cost: < $25 monthly

  • 0 helpful marks

Feb 24, 2020 (Started Jun 30, 2012)

  • Effectiveness
    Major (for insomnia)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: As needed
Advice & Tips: Pellentesque habitant morbi tristique senectus et netus et malesuada fames ac turpis egestas. Phasellus faucibus turpis sed mi maximus mattis.

Mar 17, 2015 (Started Jun 30, 2012)

  • Effectiveness
    Moderate (for insomnia)
  • Side effects
    None
  • Adherence
    Usually
  • Burden
    Not at all hard to take
Dosage: As needed
Advice & Tips: Pellentesque habitant morbi tristique senectus et netus et malesuada fames ac turpis egestas. Phasellus faucibus turpis sed mi maximus mattis.

  • 1 helpful mark
Last updated:
Showing 3 of 46 patient evaluations for Melatonin