What is Metformin?
Category: Prescription Drugs
Most popular types: Metformin ER Glucophage Diabex Show all
Metformin an antidiabetic agent used for the management of type 2 diabetes mellitus (noninsulin dependent, NIDDM) as monotherapy when hyperglycemia (high blood sugar) cannot be managed with diet and exercise alone.
| Purpose | Patients | Evaluations | Perceived Effectiveness |
|---|---|---|---|
| Diabetes type 2 | 23510 | 1096 | |
| Polycystic ovary syndrome | 684 | 119 | |
| Prediabetes | 268 | 77 | |
| Elevated blood sugar (hyperglycemia) | 32 | 56 | |
| Insulin resistance | 28 | 8 |
- Major
- Moderate
- Slight
- None
- Can't tell
Side effects
Side effects as an overall problem
| Severity | Evaluations | Percentage |
|---|---|---|
| Severe | 152 | |
| Moderate | 197 | |
| Mild | 256 | |
| None | 678 |
Commonly reported side effects and conditions associated with Metformin
| Side effect | Patients | Percentage |
|---|---|---|
| Diarrhea | 216 | |
| Nausea | 74 | |
| Stomach pain | 36 | |
| Loose bowel movements | 21 | |
| Low blood sugar (hypoglycemia) | 14 | |
| Weight gain | 13 |
Why patients stopped taking Metformin
Multiple reasons could be selected
| Reason | Patients | Percentage |
|---|---|---|
| Side effects too severe | 218 | |
| Doctor's advice | 199 | |
| Did not seem to work | 107 | |
| Other | 85 | |
| Course of treatment ended | 54 | |
| Personal research | 19 | |
| Change in health plan coverage | 15 | |
| Expense | 10 |
Duration
Stopped taking Metformin
| Duration | Patients | Percentage |
|---|---|---|
| Less than 1 month | 80 | |
| 1 - 6 months | 94 | |
| 6 months - 1 year | 52 | |
| 1 - 2 years | 66 | |
| 2 - 5 years | 112 | |
| 5 - 10 years | 78 | |
| 10 years or more | 40 |
What people switch to and from
Patients started taking Metformin after stopping:
| Treatment | Patients | Percentage |
|---|---|---|
| Glipizide (Glipizide ER) | 16 | |
| Insulin Glargine (Lantus) | 8 | |
| Glimepiride (Amaryl) | 7 | |
| Glyburide (Euglukon) | 6 | |
| Sitagliptin (Januvia) | 6 |
Patients stopped taking Metformin and switched to:
| Treatment | Patients | Percentage |
|---|---|---|
| Glipizide (Glipizide ER) | 29 | |
| Sitagliptin-metformin (Janumet) | 24 | |
| Insulin Glargine (Lantus) | 23 | |
| Glimepiride (Amaryl) | 21 | |
| Liraglutide (Victoza) | 18 |
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