What is Milnacipran?
Category: Prescription Drugs
Most popular types: Savella Ixel
Milnacipran is a serotonin/norepinephrine reuptake inhibitor (SNRI) antidepressant. It is used in the treatment of depression and has demonstrated significant improvements in multiple aspects of fibromyalgia, including pain, patient global assessment and physical function.
| Purpose | Patients | Evaluations | Perceived Effectiveness |
|---|---|---|---|
| Fibromyalgia | 3113 | 632 | |
| Pain | 199 | 101 | |
| Depressed mood | 108 | 55 | |
| Whole body joint ache | 23 | 10 | |
| Fatigue | 14 | 9 |
- Major
- Moderate
- Slight
- None
- Can't tell
Side effects
Side effects as an overall problem
| Severity | Evaluations | Percentage |
|---|---|---|
| Severe | 197 | |
| Moderate | 160 | |
| Mild | 166 | |
| None | 166 |
Commonly reported side effects and conditions associated with Milnacipran
| Side effect | Patients | Percentage |
|---|---|---|
| Nausea | 90 | |
| Excessive sweating | 38 | |
| Headaches | 29 | |
| Hot flashes | 29 | |
| Constipation | 27 | |
| Dizziness | 21 |
Why patients stopped taking Milnacipran
Multiple reasons could be selected
| Reason | Patients | Percentage |
|---|---|---|
| Side effects too severe | 277 | |
| Did not seem to work | 188 | |
| Doctor's advice | 78 | |
| Expense | 57 | |
| Other | 35 | |
| Change in health plan coverage | 19 | |
| Personal research | 14 | |
| Course of treatment ended | 7 |
Duration
Stopped taking Milnacipran
| Duration | Patients | Percentage |
|---|---|---|
| Less than 1 month | 125 | |
| 1 - 6 months | 177 | |
| 6 months - 1 year | 53 | |
| 1 - 2 years | 46 | |
| 2 - 5 years | 42 | |
| 5 - 10 years | 11 | |
| 10 years or more | 3 |
What people switch to and from
Patients started taking Milnacipran after stopping:
| Treatment | Patients | Percentage |
|---|---|---|
| Duloxetine (Cymbalta) | 34 | |
| Pregabalin (Lyrica) | 20 | |
| Gabapentin (Neurontin) | 8 | |
| Escitalopram (Lexapro) | 2 | |
| Nortriptyline (Pamelor) | 2 |
Patients stopped taking Milnacipran and switched to:
| Treatment | Patients | Percentage |
|---|---|---|
| Duloxetine (Cymbalta) | 22 | |
| Gabapentin (Neurontin) | 7 | |
| Pregabalin (Lyrica) | 6 | |
| Bupropion (Wellbutrin) | 3 | |
| Naltrexone (Low Dose Naltrexone (LDN)) | 3 |
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