What is Mitoxantrone?
Category: Prescription Drugs
Most popular types: Novantrone
See also: FCMR protocol
Mitoxantrone is an antineoplastic agent used in the treatment of acute nonlymphocytic leukemia, prostate cancer, secondary progressive or relapsing-remitting MS. It may also be used for certain lymphomas, certain adult and pediatric leukemias, myelodysplastic syndrome, breast cancer and sarcoma.
| Purpose | Patients | Evaluations | Perceived Effectiveness |
|---|---|---|---|
| Multiple sclerosis | 1153 | 80 | |
| Weakness in leg(s) | 6 | 3 | |
| Improve mobility | 4 | 5 | |
| General health | 2 | 0 | |
| Neuromyelitis optica | 2 | 0 |
- Major
- Moderate
- Slight
- None
- Can't tell
Side effects
Side effects as an overall problem
| Severity | Evaluations | Percentage |
|---|---|---|
| Severe | 18 | |
| Moderate | 24 | |
| Mild | 25 | |
| None | 19 |
Why patients stopped taking Mitoxantrone
Multiple reasons could be selected
| Reason | Patients | Percentage |
|---|---|---|
| Course of treatment ended | 106 | |
| Doctor's advice | 79 | |
| Did not seem to work | 59 | |
| Side effects too severe | 57 | |
| Other | 25 | |
| Personal research | 6 | |
| Expense | 4 | |
| Change in health plan coverage | 1 |
Duration
Stopped taking Mitoxantrone
| Duration | Patients | Percentage |
|---|---|---|
| Less than 1 month | 30 | |
| 1 - 6 months | 46 | |
| 6 months - 1 year | 52 | |
| 1 - 2 years | 52 | |
| 2 - 5 years | 46 | |
| 5 - 10 years | 5 | |
| 10 years or more | 4 |
What people switch to and from
Patients started taking Mitoxantrone after stopping:
| Treatment | Patients | Percentage |
|---|---|---|
| Interferon beta-1a IM Injection (Avonex) | 2 | |
| Interferon beta-1b SubQ Injection (Betaseron) | 2 | |
| Natalizumab (Tysabri) | 2 | |
| Glatiramer acetate (Copaxone) | 1 | |
| Interferon beta-1a SubQ injection (Rebif) | 1 |
Patients stopped taking Mitoxantrone and switched to:
| Treatment | Patients | Percentage |
|---|---|---|
| Glatiramer acetate (Copaxone) | 3 | |
| Natalizumab (Tysabri) | 3 | |
| Fingolimod (Gilenya) | 1 | |
| Naltrexone (Low Dose Naltrexone (LDN)) | 1 | |
| Stem Cell Transplant (Autologous Stem Cell Transplant) | 1 |
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