What is Rituximab?
Category: Prescription Drugs
Most popular types: Rituxan Mabthera
See also: DRC protocol FCMR protocol ILD Phase II/III Rituximab Versus Cyclophosphamide RECITAL Study R-CVP protocol RT protocol
Rituximab is a medication in a class of medications called monoclonal antibodies and given by infusion. It is used in the treatment of non-Hodgkins lymphoma and also in the treatment of rheumatoid arthritis.
| Purpose | Patients | Evaluations | Perceived Effectiveness |
|---|---|---|---|
| Rheumatoid arthritis | 886 | 49 | |
| Neuromyelitis optica | 190 | 41 | |
| Chronic lymphocytic leukemia | 165 | 11 | |
| Multiple sclerosis | 155 | 90 | |
| Follicular lymphoma | 62 | 10 | |
| Mantle cell lymphoma | 40 | 3 |
- Major
- Moderate
- Slight
- None
- Can't tell
Side effects
Side effects as an overall problem
| Severity | Evaluations | Percentage |
|---|---|---|
| Severe | 39 | |
| Moderate | 44 | |
| Mild | 89 | |
| None | 89 |
Why patients stopped taking Rituximab
Multiple reasons could be selected
| Reason | Patients | Percentage |
|---|---|---|
| Course of treatment ended | 59 | |
| Did not seem to work | 40 | |
| Doctor's advice | 29 | |
| Side effects too severe | 29 | |
| Other | 21 | |
| Change in health plan coverage | 5 | |
| Expense | 4 | |
| Personal research | 3 |
Duration
Stopped taking Rituximab
| Duration | Patients | Percentage |
|---|---|---|
| Less than 1 month | 66 | |
| 1 - 6 months | 31 | |
| 6 months - 1 year | 20 | |
| 1 - 2 years | 17 | |
| 2 - 5 years | 22 | |
| 5 - 10 years | 2 | |
| 10 years or more | 2 |
What people switch to and from
Patients started taking Rituximab after stopping:
| Treatment | Patients | Percentage |
|---|---|---|
| Natalizumab (Tysabri) | 21 | |
| Glatiramer acetate (Copaxone) | 19 | |
| Dimethyl fumarate (Tecfidera) | 12 | |
| Abatacept (Orencia) | 10 | |
| Fingolimod (Gilenya) | 10 |
Patients stopped taking Rituximab and switched to:
| Treatment | Patients | Percentage |
|---|---|---|
| Ocrelizumab (Ocrevus) | 8 | |
| Tocilizumab (Actemra) | 6 | |
| Mycophenolate mofetil (CellCept) | 5 | |
| Abatacept (Orencia) | 4 | |
| Natalizumab (Tysabri) | 4 |
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