What is Rotigotine?
Category: Prescription Drugs
Most popular types: Neupro Patch
Rotigotine, a dopamine agonist drug delivered slowly across the skin by means of a transdermal patch, is worn for 24hrs at a time. The aim is to provide a slow, steady stream of dopamine in order to reduce symptoms and on/off fluctuations.
| Purpose | Patients | Evaluations | Perceived Effectiveness |
|---|---|---|---|
| Parkinson's disease | 1958 | 210 | |
| Restless legs syndrome | 29 | 22 | |
| Stiffness/spasticity | 21 | 10 | |
| Tremor in hands | 5 | 18 | |
| Tremor(s) | 4 | 2 | |
| Essential tremor | 2 | 1 |
- Major
- Moderate
- Slight
- None
- Can't tell
Side effects
Side effects as an overall problem
| Severity | Evaluations | Percentage |
|---|---|---|
| Severe | 19 | |
| Moderate | 53 | |
| Mild | 64 | |
| None | 90 |
Commonly reported side effects and conditions associated with Rotigotine
| Side effect | Patients | Percentage |
|---|---|---|
| Nausea | 14 | |
| Skin irritation under patch | 8 | |
| Itching | 5 | |
| Anxious mood | 4 | |
| Fatigue | 4 | |
| Headaches | 4 |
Why patients stopped taking Rotigotine
Multiple reasons could be selected
| Reason | Patients | Percentage |
|---|---|---|
| Other | 68 | |
| Side effects too severe | 68 | |
| Did not seem to work | 53 | |
| Doctor's advice | 38 | |
| Expense | 13 | |
| Course of treatment ended | 8 | |
| Personal research | 4 | |
| Change in health plan coverage | 2 |
Duration
Stopped taking Rotigotine
| Duration | Patients | Percentage |
|---|---|---|
| Less than 1 month | 47 | |
| 1 - 6 months | 65 | |
| 6 months - 1 year | 43 | |
| 1 - 2 years | 24 | |
| 2 - 5 years | 13 | |
| 5 - 10 years | 2 | |
| 10 years or more | 2 |
What people switch to and from
Patients started taking Rotigotine after stopping:
| Treatment | Patients | Percentage |
|---|---|---|
| Pramipexole (Mirapex) | 20 | |
| Ropinirole (Requip) | 16 | |
| Carbidopa-Levodopa (Sinemet) | 6 | |
| Amantadine (Symmetrel) | 3 | |
| Carbidopa-Entacapone-Levodopa (Stalevo) | 2 |
Patients stopped taking Rotigotine and switched to:
| Treatment | Patients | Percentage |
|---|---|---|
| Carbidopa-Levodopa (Sinemet) | 16 | |
| Ropinirole (Requip) | 15 | |
| Pramipexole (Mirapex) | 11 | |
| Carbidopa Levodopa ER (Rytary XR) | 4 | |
| Amantadine (Symmetrel) | 1 |
Last updated: