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What is Sirolimus?

Category: Prescription Drugs

Most popular types: Rapamune Rocas

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Sirolimus is an immunosuppressant agent used to prevent organ rejection in renal transplants, in combination with corticosteroids and cyclosporine. It is also used to prevent rejection in heart transplant and for immunosuppression for stem cell/bone marrow transplants.

See patients taking Sirolimus

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Prevent organ rejection 190 22
Kidney transplant 11 2
Graft versus host disease 9 0
Lung transplant 3 0
Heart transplant 2 0

Show all 12 reasons taken

  • Major
  • Moderate
  • Slight
  • None
  • Can't tell
See all 390 patients that have taken Sirolimus

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations Percentage
Severe 10
Moderate 10
Mild 7
None 8

Commonly reported side effects and conditions associated with Sirolimus

Side effect Patients Percentage
Acne breakout 3
Chronic diarrhea 3
Mouth sores (ulcers) 3
Fluid retention (edema) 2
High cholesterol (hypercholesterolemia) 2
Increased lipids in blood (hyperlipidemia) 2

Show all 24 reported side effects

Why patients stopped taking Sirolimus

Multiple reasons could be selected

Reason Patients Percentage
Doctor's advice 17
Side effects too severe 16
Did not seem to work 4
Course of treatment ended 3
Personal research 3
Other 2
Change in health plan coverage 1
See all 31 patients who've stopped taking Sirolimus

Duration

Stopped taking Sirolimus

Duration Patients Percentage
Less than 1 month 7
1 - 6 months 9
6 months - 1 year 4
1 - 2 years 1
2 - 5 years 2
5 - 10 years 3
Adherence
Adherence Evaluations Percentage
Always 31
Usually 4
Sometimes 0
Never taken as prescribed 0
Burden
Burden Evaluations Percentage
Very hard to take 1
Somewhat hard to take 5
A little hard to take 2
Not at all hard to take 27
Cost per month
Cost per month Evaluations Percentage
$200+ 1
$100-199 1
$50-99 4
$25-49 1
< $25 7
Not specified 21

What people switch to and from

Patients started taking Sirolimus after stopping:

Treatment Patients Percentage
Tacrolimus (Prograf) 2
Belimumab (Benlysta) 1
Cyclosporine (Neoral) 1
Mycophenolate mofetil (CellCept) 1
Mycophenolic acid (Myfortic) 1

Patients stopped taking Sirolimus and switched to:

Treatment Patients Percentage
Mycophenolic acid (Myfortic) 1
Tacrolimus (Prograf) 1
Last updated:

3 patient evaluations for Sirolimus

Sort by: Most recent

Jun 17, 2012 (Started Jul 18, 2011)

  • Effectiveness
    Can't tell (for Prevent organ rejection)
  • Side effects
    Moderate (swelling in lower extremities)
  • Adherence
    Usually
  • Burden
    Somewhat hard to take
Dosage: 0.5 mg Daily
Side effects: swelling in lower extremities
  • 0 helpful marks

Jul 14, 2010 (Started Jul 21, 1998)

  • Effectiveness
    Major (for transplant rejection prevention)
  • Side effects
    Severe (recurrent hernias)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 2 mg Daily
Advice & Tips: Pellentesque habitant morbi tristique senectus et netus et malesuada fames ac turpis egestas. Phasellus faucibus turpis sed mi maximus mattis.
Cost: $200+ monthly
Side effects: recurrent hernias
  • 0 helpful marks

Mar 17, 2010 (Started Dec 17, 2003)

  • Effectiveness
    Major (for transplant rejection prevention)
  • Side effects
    Moderate (swelling in feet)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 1 mg Daily
Advice & Tips: Pellentesque habitant morbi tristique senectus et netus et malesuada fames ac turpis egestas. Phasellus faucibus turpis sed mi maximus mattis.
Side effects: swelling in feet
  • 0 helpful marks
Last updated:
Showing 3 of 3 patient evaluations for Sirolimus