What is Tamoxifen?
Category: Prescription Drugs
Most popular types: Tamoxol Nolvadex Istubal Show all
Tamoxifen is an oral selective estrogen receptor modulator which is used in breast cancer treatment, and is currently the world's largest selling breast cancer treatment. It is used for the treatment of early and advanced breast cancer. It is undergoing trials in ALS/MND under Prof Ben Brooks.
| Purpose | Patients | Evaluations | Perceived Effectiveness |
|---|---|---|---|
| Breast cancer | 134 | 44 | |
| Amyotrophic lateral sclerosis | 16 | 7 | |
| Atypical hyperplasia of breast | 4 | 4 | |
| Familial adenomatous polyposis | 3 | 0 | |
| Gynecomastia | 2 | 1 |
- Major
- Moderate
- Slight
- None
- Can't tell
Side effects
Side effects as an overall problem
| Severity | Evaluations | Percentage |
|---|---|---|
| Severe | 21 | |
| Moderate | 18 | |
| Mild | 15 | |
| None | 13 |
Commonly reported side effects and conditions associated with Tamoxifen
| Side effect | Patients | Percentage |
|---|---|---|
| Hot flashes | 12 | |
| Fatigue | 7 | |
| Weight gain | 6 | |
| Night sweats | 5 | |
| Bone pain | 3 | |
| Nausea | 3 |
Duration
Stopped taking Tamoxifen
| Duration | Patients | Percentage |
|---|---|---|
| Less than 1 month | 7 | |
| 1 - 6 months | 12 | |
| 6 months - 1 year | 5 | |
| 1 - 2 years | 4 | |
| 2 - 5 years | 14 | |
| 5 - 10 years | 1 |
What people switch to and from
Patients started taking Tamoxifen after stopping:
| Treatment | Patients | Percentage |
|---|---|---|
| Chemotherapy | 5 | |
| Anastrozole (Arimidex) | 2 | |
| Paclitaxel (Taxol) | 1 |
Patients stopped taking Tamoxifen and switched to:
| Treatment | Patients | Percentage |
|---|---|---|
| Anastrozole (Arimidex) | 9 | |
| Exemestane (Aromasin) | 4 | |
| Letrozole (Femara) | 4 | |
| Capecitabine (Xeloda) | 1 | |
| Carboplatin | 1 |
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