What is Tofacitinib?
Category: Prescription Drugs
Most popular types: Xeljanz Xeljanz XR
Tofacitinib is an oral medication that is known as a disease modifying antirheumatic drug. It is used in the treatment of adult patients with moderately- to severely-active rheumatoid arthritis who are unable to take or who have had an inadequate response to methotrexate.
| Purpose | Patients | Evaluations | Perceived Effectiveness |
|---|---|---|---|
| Rheumatoid arthritis | 1228 | 27 | |
| Ulcerative colitis | 6 | 0 | |
| Stiffness in morning | 4 | 0 | |
| Psoriatic arthritis | 3 | 1 | |
| Pain | 2 | 1 | |
| Alopecia areata | 1 | 1 |
- Major
- Moderate
- Slight
- None
- Can't tell
Side effects
Side effects as an overall problem
| Severity | Evaluations | Percentage |
|---|---|---|
| Severe | 5 | |
| Moderate | 2 | |
| Mild | 5 | |
| None | 21 |
Commonly reported side effects and conditions associated with Tofacitinib
| Side effect | Patients | Percentage |
|---|---|---|
| Headaches | 4 | |
| High cholesterol (hypercholesterolemia) | 2 | |
| Stomach pain | 2 | |
| Biliary reflux | 1 | |
| Dizziness | 1 | |
| Fatigue | 1 |
Duration
Stopped taking Tofacitinib
| Duration | Patients | Percentage |
|---|---|---|
| Less than 1 month | 7 | |
| 1 - 6 months | 6 | |
| 6 months - 1 year | 1 | |
| 1 - 2 years | 3 | |
| 2 - 5 years | 1 |
What people switch to and from
Patients started taking Tofacitinib after stopping:
| Treatment | Patients | Percentage |
|---|---|---|
| Adalimumab (Humira) | 13 | |
| Methotrexate (Apo-Methotrexate) | 11 | |
| Tocilizumab (Actemra) | 9 | |
| Etanercept (Enbrel) | 8 | |
| Leflunomide (Arava) | 5 |
Patients stopped taking Tofacitinib and switched to:
| Treatment | Patients | Percentage |
|---|---|---|
| Abatacept (Orencia) | 6 | |
| Etanercept (Enbrel) | 5 | |
| Adalimumab (Humira) | 4 | |
| Methotrexate (Apo-Methotrexate) | 3 | |
| Rituximab (Rituxan) | 2 |
Last updated: