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What is Tolcapone?

Category: Prescription Drugs

Most popular types: Tasmar

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Tolcapone is a COMT inhibitor which promotes the recirculation of dopamine at the synapse. It is used in conjunction with l-dopa containing medication such as Sinemet.

See patients taking Tolcapone

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Parkinson's disease 15 8
Increase effect of another treatment 3 6
  • Major
  • Moderate
  • Slight
  • None
  • Can't tell
See all 28 patients that have taken Tolcapone

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations Percentage
Severe 3
Moderate 1
Mild 2
None 8

Commonly reported side effects and conditions associated with Tolcapone

Side effect Patients Percentage
Constipation 1
Diarrhea 1
Difficulty thinking 1
Dizziness 1
Dry mouth 1
Flatulence 1

Show all 18 reported side effects

Why patients stopped taking Tolcapone

Multiple reasons could be selected

Reason Patients Percentage
Expense 3
Side effects too severe 2
Change in health plan coverage 1
Did not seem to work 1
Doctor's advice 1
Personal research 1
See all 4 patients who've stopped taking Tolcapone

Duration

Stopped taking Tolcapone

Duration Patients Percentage
1 - 6 months 2
2 - 5 years 1
5 - 10 years 1
Adherence
Adherence Evaluations Percentage
Always 12
Usually 1
Sometimes 0
Never taken as prescribed 1
Burden
Burden Evaluations Percentage
Very hard to take 1
Somewhat hard to take 0
A little hard to take 3
Not at all hard to take 10
Cost per month
Cost per month Evaluations Percentage
$200+ 3
$100-199 0
$50-99 4
$25-49 2
< $25 3
Not specified 2

What people switch to and from

Patients started taking Tolcapone after stopping:

Treatment Patients Percentage
Amantadine (Symmetrel) 1
Ropinirole (Requip) 1

Patients stopped taking Tolcapone and switched to:

Treatment Patients Percentage
Entacapone (Comtan) 1
Last updated:
There are no evaluations for Tolcapone.