What is Trihexyphenidyl?

Category: Prescription Drugs

Most popular types: Artane Trihexyphen Pacitane Show all

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See also: Risperidone-Trihexyphenidyl Rispond Plus

Trihexyphenidyl is anti-Parkinson's and anticholinergic agent used as adjunctive treatment of Parkinson's disease and for the treatment of drug-induced extrapyramidal symptoms.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Parkinson's disease 88 50
Tremor in hands 30 22
Tremor(s) 24 26
Torticollis 10 0
Dystonia 5 6
Restlessness (akathisia) 5 4

Show all 29 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations Percentage
Severe 19
Moderate 32
Mild 29
None 28

Commonly reported side effects and conditions associated with Trihexyphenidyl

Side effect Patients Percentage
Cognitive confusion 10
Dry mouth 9
Word fishing 6
Dizziness 4
Sleepiness 4
Auditory hallucinations 2

Show all 47 reported side effects

Why patients stopped taking Trihexyphenidyl

Multiple reasons could be selected

Reason Patients Percentage
Side effects too severe 30
Doctor's advice 20
Did not seem to work 18
Other 10
Course of treatment ended 3
Personal research 3
Expense 1
See all 63 patients who've stopped taking Trihexyphenidyl

Duration

Stopped taking Trihexyphenidyl

Duration Patients Percentage
Less than 1 month 6
1 - 6 months 21
6 months - 1 year 11
1 - 2 years 11
2 - 5 years 11
5 - 10 years 1
10 years or more 3
Adherence
Adherence Evaluations Percentage
Always 72
Usually 24
Sometimes 3
Never taken as prescribed 9
Burden
Burden Evaluations Percentage
Very hard to take 5
Somewhat hard to take 6
A little hard to take 20
Not at all hard to take 77
Cost per month
Cost per month Evaluations Percentage
$200+ 0
$100-199 1
$50-99 0
$25-49 6
< $25 62
Not specified 39

What people switch to and from

Patients started taking Trihexyphenidyl after stopping:

Treatment Patients Percentage
Baclofen (Mylan-Baclofen) 1
Benztropine (Cogentin) 1
Biperiden (Akineton) 1
Cyclobenzaprine (Flexeril) 1
Gabapentin (Neurontin) 1

Show all 11 treatments patients report switching from

Patients stopped taking Trihexyphenidyl and switched to:

Treatment Patients Percentage
Carbidopa-Levodopa (Sinemet) 5
Amantadine (Symmetrel) 2
Entacapone (Comtan) 2
Baclofen (Mylan-Baclofen) 1
Cyclobenzaprine (Flexeril) 1

Show all 7 treatments patients report switching to

Last updated:

10 patient evaluations for Trihexyphenidyl

Jan 9, 2016 (Started Dec 20, 2011)

  • Effectiveness
    Moderate (for Parkinson's disease)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 6 mg Daily
Cost: < $25 monthly

  • 0 helpful marks

May 13, 2012 (Started Apr 28, 2010)

  • Effectiveness
    Moderate (for pd was progressing)
  • Side effects
    Moderate (complete exhaustion, anxious mood)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 2.5 mg Daily
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Cost: < $25 monthly

  • 0 helpful marks

Mar 25, 2011 (Started Oct 12, 2003)

  • Effectiveness
    Moderate (for Parkinson's disease)
  • Side effects
    Severe (cognitive confusion, loss of short term memory)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 20 mg Daily
Advice & Tips: Pellentesque habitant morbi tristique senectus et netus et malesuada fames ac turpis egestas. Phasellus faucibus turpis sed mi maximus mattis.
Cost: < $25 monthly
Side effects: cognitive confusion, loss of short term memory

Jan 3, 2011 (Started Oct 12, 2003)

  • Effectiveness
    Major (for Parkinson's disease)
  • Side effects
    Moderate (cognitive confusion, loss of short term memory)
  • Adherence
    Usually
  • Burden
    Somewhat hard to take
Dosage: 20 mg Daily
Advice & Tips: Pellentesque habitant morbi tristique senectus et netus et malesuada fames ac turpis egestas. Phasellus faucibus turpis sed mi maximus mattis.
Cost: < $25 monthly
Side effects: cognitive confusion, loss of short term memory

Apr 2, 2010 (Started Oct 12, 2003)

  • Effectiveness
    Major (for Parkinson's disease)
  • Side effects
    Moderate (cognitive confusion, loss of short term memory)
  • Adherence
    Usually
  • Burden
    A little hard to take
Dosage: 20 mg Daily
Advice & Tips: Pellentesque habitant morbi tristique senectus et netus et malesuada fames ac turpis egestas. Phasellus faucibus turpis sed mi maximus mattis.
Cost: < $25 monthly
Side effects: cognitive confusion, loss of short term memory

Nov 20, 2009 (Started Oct 12, 2003)

  • Effectiveness
    Major (for Parkinson's disease)
  • Side effects
    Severe (cognitive confusion)
  • Adherence
    Always
  • Burden
    A little hard to take
Dosage: 20 mg Daily
Advice & Tips: Pellentesque habitant morbi tristique senectus et netus et malesuada fames ac turpis egestas. Phasellus faucibus turpis sed mi maximus mattis.
Cost: < $25 monthly
Side effects: cognitive confusion, loss of short term memory

  • 1 helpful mark
Last updated:
Showing 3 of 10 patient evaluations for Trihexyphenidyl