What is Duloxetine?
Category: Prescription Drugs
Most popular types: Cymbalta Yentreve Cymgen Show all
Duloxetine is a selective serotonin and norepinephrine reuptake inhibitor (SSNRI). It may be used for depression, general anxiety disorder, pain associated with diabetic neuropathy and fibromyalgia.
| Purpose | Patients | Evaluations | Perceived Effectiveness |
|---|---|---|---|
| Fibromyalgia | 45438 | 3388 | |
| Major depressive disorder | 10785 | 1245 | |
| Depressed mood | 2384 | 1284 | |
| Generalized anxiety disorder | 2069 | 580 | |
| Myalgic encephalomyelitis/chronic fatigue syndrome | 1867 | 379 | |
| Persistent depressive disorder (dysthymia) | 632 | 150 |
- Major
- Moderate
- Slight
- None
- Can't tell
Side effects
Side effects as an overall problem
| Severity | Evaluations | Percentage |
|---|---|---|
| Severe | 962 | |
| Moderate | 1058 | |
| Mild | 1208 | |
| None | 1972 |
Commonly reported side effects and conditions associated with Duloxetine
| Side effect | Patients | Percentage |
|---|---|---|
| Weight gain | 344 | |
| Nausea | 303 | |
| Decreased sex drive (libido) | 192 | |
| Dry mouth | 179 | |
| Dizziness | 168 | |
| Brain fog | 119 |
Why patients stopped taking Duloxetine
Multiple reasons could be selected
| Reason | Patients | Percentage |
|---|---|---|
| Side effects too severe | 1875 | |
| Did not seem to work | 1738 | |
| Doctor's advice | 647 | |
| Other | 484 | |
| Expense | 468 | |
| Personal research | 198 | |
| Change in health plan coverage | 168 | |
| Course of treatment ended | 76 |
Duration
Stopped taking Duloxetine
| Duration | Patients | Percentage |
|---|---|---|
| Less than 1 month | 831 | |
| 1 - 6 months | 935 | |
| 6 months - 1 year | 557 | |
| 1 - 2 years | 502 | |
| 2 - 5 years | 554 | |
| 5 - 10 years | 177 | |
| 10 years or more | 59 |
What people switch to and from
Patients started taking Duloxetine after stopping:
| Treatment | Patients | Percentage |
|---|---|---|
| Pregabalin (Lyrica) | 165 | |
| Fluoxetine (Prozac) | 161 | |
| Venlafaxine (Effexor XR) | 142 | |
| Sertraline (Zoloft) | 130 | |
| Citalopram (Celexa) | 111 |
Patients stopped taking Duloxetine and switched to:
| Treatment | Patients | Percentage |
|---|---|---|
| Pregabalin (Lyrica) | 111 | |
| Venlafaxine (Effexor XR) | 109 | |
| Gabapentin (Neurontin) | 88 | |
| Bupropion (Wellbutrin) | 64 | |
| Fluoxetine (Prozac) | 55 |
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