What is Insulin Glargine?
Category: Prescription Drugs
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Insulin glargine is a long acting insulin used for the treatment of type 1 diabetes mellitus (insulin dependent, IDDM) and type 2 diabetes mellitus (non-insulin dependent, NIDDM) requiring basal (long-acting) insulin to improve glycemic control.
| Purpose | Patients | Evaluations | Perceived Effectiveness |
|---|---|---|---|
| Diabetes type 2 | 8571 | 246 | |
| Diabetes type 1 | 1374 | 35 | |
| Cystic fibrosis-related diabetes | 11 | 3 | |
| General health | 9 | 3 | |
| Elevated blood sugar (hyperglycemia) | 7 | 1 | |
| Increase effect of another treatment | 4 | 0 |
- Major
- Moderate
- Slight
- None
- Can't tell
Side effects
Side effects as an overall problem
| Severity | Evaluations | Percentage |
|---|---|---|
| Severe | 3 | |
| Moderate | 21 | |
| Mild | 55 | |
| None | 204 |
Commonly reported side effects and conditions associated with Insulin Glargine
| Side effect | Patients | Percentage |
|---|---|---|
| Low blood sugar (hypoglycemia) | 14 | |
| Weight gain | 11 | |
| Nausea | 4 | |
| Reactive hypoglycemia | 4 | |
| Burning pain at injection site | 3 | |
| Injection site pain | 3 |
Why patients stopped taking Insulin Glargine
Multiple reasons could be selected
| Reason | Patients | Percentage |
|---|---|---|
| Doctor's advice | 64 | |
| Other | 44 | |
| Did not seem to work | 33 | |
| Course of treatment ended | 24 | |
| Side effects too severe | 15 | |
| Change in health plan coverage | 12 | |
| Expense | 12 | |
| Personal research | 3 |
Duration
Stopped taking Insulin Glargine
| Duration | Patients | Percentage |
|---|---|---|
| Less than 1 month | 27 | |
| 1 - 6 months | 22 | |
| 6 months - 1 year | 15 | |
| 1 - 2 years | 16 | |
| 2 - 5 years | 33 | |
| 5 - 10 years | 23 | |
| 10 years or more | 8 |
What people switch to and from
Patients started taking Insulin Glargine after stopping:
| Treatment | Patients | Percentage |
|---|---|---|
| Metformin (Metformin ER) | 23 | |
| Glipizide (Glipizide ER) | 9 | |
| insulin detemir (Levemir) | 9 | |
| Glimepiride (Amaryl) | 6 | |
| Insulin NPH (Novolin N) | 5 |
Patients stopped taking Insulin Glargine and switched to:
| Treatment | Patients | Percentage |
|---|---|---|
| insulin detemir (Levemir) | 15 | |
| Insulin degludec (Tresiba) | 14 | |
| Metformin (Metformin ER) | 8 | |
| Insulin Aspart (Novolog) | 7 | |
| Insulin Lispro (Humalog) | 6 |
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