What is Lacosamide?
Category: Prescription Drugs
Most popular types: Vimpat
Lacosamide is an anticonvulsant agent used for adjunctive therapy in the treatment of partial-onset seizures. Lacosamide was previously known as harkoseride and then SPM 927.
| Purpose | Patients | Evaluations | Perceived Effectiveness |
|---|---|---|---|
| Epilepsy | 1123 | 215 | |
| Seizures (complex partial) | 64 | 75 | |
| Seizures | 24 | 9 | |
| Muscle tightness with stiffness | 4 | 1 | |
| Nerve pain (neuralgia) | 4 | 1 | |
| Seizures (grand mal or tonic-clonic) | 3 | 0 |
- Major
- Moderate
- Slight
- None
- Can't tell
Side effects
Side effects as an overall problem
| Severity | Evaluations | Percentage |
|---|---|---|
| Severe | 49 | |
| Moderate | 59 | |
| Mild | 75 | |
| None | 51 |
Commonly reported side effects and conditions associated with Lacosamide
| Side effect | Patients | Percentage |
|---|---|---|
| Dizziness | 17 | |
| Double vision (diplopia) | 12 | |
| Blurry vision | 8 | |
| Drowsiness | 6 | |
| Excessive daytime sleepiness (somnolence) | 6 | |
| Headaches | 6 |
Why patients stopped taking Lacosamide
Multiple reasons could be selected
| Reason | Patients | Percentage |
|---|---|---|
| Did not seem to work | 49 | |
| Side effects too severe | 41 | |
| Doctor's advice | 27 | |
| Expense | 11 | |
| Other | 7 | |
| Change in health plan coverage | 2 | |
| Course of treatment ended | 2 |
Duration
Stopped taking Lacosamide
| Duration | Patients | Percentage |
|---|---|---|
| Less than 1 month | 19 | |
| 1 - 6 months | 32 | |
| 6 months - 1 year | 15 | |
| 1 - 2 years | 8 | |
| 2 - 5 years | 13 | |
| 5 - 10 years | 1 |
What people switch to and from
Patients started taking Lacosamide after stopping:
| Treatment | Patients | Percentage |
|---|---|---|
| Levetiracetam (Keppra) | 10 | |
| Topiramate (Topamax) | 7 | |
| Lamotrigine (Lamictal) | 3 | |
| Divalproex sodium (Depakote) | 2 | |
| Carbamazepine (Tegretol) | 1 |
Patients stopped taking Lacosamide and switched to:
| Treatment | Patients | Percentage |
|---|---|---|
| Levetiracetam (Keppra) | 5 | |
| Topiramate (Topamax) | 3 | |
| Divalproex sodium (Depakote) | 2 | |
| Brivaracetam (Briviact) | 1 | |
| Clobazam (Onfi) | 1 |
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