What is Levothyroxine?

Category: Prescription Drugs

Most popular types: Synthroid Thyroxine Levoxyl Show all

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See also: Thyrolar-1

Levothyroxine is a synthetic form of the human hormone thyroxine. The drug is used to treat hypothyroidism (underactive thyroid), which can lead to weight gain, depression, and pain.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Hypothyroidism 5244 1107
Hashimoto's thyroiditis 1490 217
Thyroid cancer 333 32
General health 148 20
Fatigue 41 20

Show all 99 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations Percentage
Severe 45
Moderate 112
Mild 130
None 1131

Commonly reported side effects and conditions associated with Levothyroxine

Side effect Patients Percentage
Weight gain 34
Fatigue 32
Hair loss 28
Headaches 17
Heart palpitations 14
Nausea 12

Show all 169 reported side effects

Why patients stopped taking Levothyroxine

Multiple reasons could be selected

Reason Patients Percentage
Did not seem to work 107
Doctor's advice 83
Other 73
Side effects too severe 56
Personal research 43
Change in health plan coverage 22
Course of treatment ended 19
Expense 13
See all 314 patients who've stopped taking Levothyroxine

Duration

Stopped taking Levothyroxine

Duration Patients Percentage
Less than 1 month 31
1 - 6 months 55
6 months - 1 year 41
1 - 2 years 34
2 - 5 years 57
5 - 10 years 46
10 years or more 59
Adherence
Adherence Evaluations Percentage
Always 1220
Usually 160
Sometimes 9
Never taken as prescribed 29
Burden
Burden Evaluations Percentage
Very hard to take 27
Somewhat hard to take 97
A little hard to take 212
Not at all hard to take 1082
Cost per month
Cost per month Evaluations Percentage
$200+ 2
$100-199 2
$50-99 13
$25-49 64
< $25 826
Not specified 511

What people switch to and from

Patients started taking Levothyroxine after stopping:

Treatment Patients Percentage
Desiccated thyroid (Armour Thyroid) 32
Levothyroxine (Synthroid) 12
Liothyronine (T3) (Cytomel) 7
Amitriptyline (Elavil) 2
Carbimazole 2

Show all 12 treatments patients report switching from

Patients stopped taking Levothyroxine and switched to:

Treatment Patients Percentage
Desiccated thyroid (Armour Thyroid) 98
Levothyroxine (Synthroid) 12
Liothyronine (T3) (Cytomel) 10
Amitriptyline (Elavil) 1
Bupropion (Wellbutrin) 1

Show all 13 treatments patients report switching to

Last updated:

95 patient evaluations for Levothyroxine

Nov 21, 2020 (Started Mar 15, 2013)

  • Effectiveness
    Major (for hypothyroidism)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 100 mcg (0.1 mg) Daily

Oct 9, 2020 (Started Mar 15, 2013)

  • Effectiveness
    Major (for hypothyroidism)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 100 mcg (0.1 mg) Daily

Aug 17, 2016 (Started Mar 15, 2013)

  • Effectiveness
    Major (for hypothyroidism)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 100 mcg (0.1 mg) Daily

  • 0 helpful marks

Apr 3, 2020 (Started Jun 15, 2016)

  • Effectiveness
    Moderate (for hypothyroidism)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 0.025 mg Daily
Cost: < $25 monthly

Jan 6, 2019 (Started Jun 15, 2016)

  • Effectiveness
    Can't tell (for hypothyroidism)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 0.025 mg Daily
Cost: < $25 monthly

Feb 21, 2018 (Started Jun 15, 2016)

  • Effectiveness
    Major (for hypothyroidism)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 0.025 mg Daily

  • 0 helpful marks

Dec 8, 2019 (Started Jul 01, 1993)

  • Effectiveness
    Major (for Hashimoto's thyroiditis)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 100 mcg (0.1 mg) Daily
Cost: < $25 monthly

Jul 8, 2018 (Started Jul 01, 1993)

  • Effectiveness
    Major (for Hashimoto's thyroiditis)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 100 mcg (0.1 mg) Daily
Cost: < $25 monthly

  • 0 helpful marks
Last updated:
Showing 3 of 95 patient evaluations for Levothyroxine