What is Naltrexone?

Category: Prescription Drugs

Most popular types: Low Dose Naltrexone (LDN) Vivitrol ReVia

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Naltrexone, in low doses such as 3mg to 4.5mg, has been found to boost the immune system in MS, autoimmune diseases, and central nervous system disorders.

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Multiple sclerosis 478 366
Fibromyalgia 204 273
Fatigue 153 197
Pain 57 65
Myalgic encephalomyelitis/chronic fatigue syndrome 46 96
Amyotrophic lateral sclerosis 42 39

Show all 187 reasons taken


  • Major
  • Moderate
  • Slight
  • None
  • Can't tell

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations Percentage
Severe 48
Moderate 70
Mild 245
None 652

Commonly reported side effects and conditions associated with Naltrexone

Side effect Patients Percentage
Vivid dreams 35
Nausea 18
Headaches 14
Insomnia 14
Insomnia 13
Diarrhea 9

Show all 134 reported side effects

Why patients stopped taking Naltrexone

Multiple reasons could be selected

Reason Patients Percentage
Did not seem to work 152
Other 71
Side effects too severe 55
Doctor's advice 43
Expense 20
Personal research 11
Course of treatment ended 10
Change in health plan coverage 3
See all 289 patients who've stopped taking Naltrexone

Duration

Stopped taking Naltrexone

Duration Patients Percentage
Less than 1 month 44
1 - 6 months 91
6 months - 1 year 37
1 - 2 years 64
2 - 5 years 42
5 - 10 years 13
Adherence
Adherence Evaluations Percentage
Always 853
Usually 123
Sometimes 16
Never taken as prescribed 23
Burden
Burden Evaluations Percentage
Very hard to take 17
Somewhat hard to take 47
A little hard to take 128
Not at all hard to take 823
Cost per month
Cost per month Evaluations Percentage
$200+ 8
$100-199 28
$50-99 111
$25-49 484
< $25 256
Not specified 128

What people switch to and from

Patients started taking Naltrexone after stopping:

Treatment Patients Percentage
Pregabalin (Lyrica) 8
Tramadol (Ultram) 8
Gabapentin (Neurontin) 7
Duloxetine (Cymbalta) 6
Hydrocodone-Acetaminophen (Norco) 5

Show all 47 treatments patients report switching from

Patients stopped taking Naltrexone and switched to:

Treatment Patients Percentage
Dimethyl fumarate (Tecfidera) 2
Acamprosate (Campral) 1
Alemtuzumab (Lemtrada) 1
Buprenorphine-Naloxone (Suboxone) 1
Carbidopa-Levodopa (Sinemet) 1

Show all 20 treatments patients report switching to

Last updated:

79 patient evaluations for Naltrexone

Jul 31, 2020 (Started Jan 31, 2015)

  • Effectiveness
    Major (for migraine headaches)
  • Effectiveness
    Slight (for rheumatoid arthritis)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 5.5 mg Twice daily
Advice & Tips: Pellentesque habitant morbi tristique senectus et netus et malesuada fames ac turpis egestas. Phasellus faucibus turpis sed mi maximus mattis.
Cost: < $25 monthly

Dec 30, 2018 (Started Jan 31, 2015)

  • Effectiveness
    Slight (for rheumatoid arthritis)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 5 mg Daily
Advice & Tips: Pellentesque habitant morbi tristique senectus et netus et malesuada fames ac turpis egestas. Phasellus faucibus turpis sed mi maximus mattis.
Cost: < $25 monthly

Aug 17, 2017 (Started Jan 31, 2015)

  • Effectiveness
    Slight (for rheumatoid arthritis)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 3.3 mg Daily
Advice & Tips: Pellentesque habitant morbi tristique senectus et netus et malesuada fames ac turpis egestas. Phasellus faucibus turpis sed mi maximus mattis.
Cost: < $25 monthly

Mar 21, 2017 (Started Jan 31, 2015)

  • Effectiveness
    Slight (for rheumatoid arthritis)
  • Side effects
    None
  • Adherence
    Usually
  • Burden
    Not at all hard to take
Dosage: 4.5 mg Daily
Advice & Tips: Pellentesque habitant morbi tristique senectus et netus et malesuada fames ac turpis egestas. Phasellus faucibus turpis sed mi maximus mattis.
Cost: < $25 monthly

Dec 31, 2016 (Started Jan 31, 2015)

  • Effectiveness
    Can't tell (for rheumatoid arthritis)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 2.2 mg Daily
Advice & Tips: Pellentesque habitant morbi tristique senectus et netus et malesuada fames ac turpis egestas. Phasellus faucibus turpis sed mi maximus mattis.
Cost: < $25 monthly

Sep 1, 2016 (Started Jan 31, 2015)

  • Effectiveness
    Can't tell (for rheumatoid arthritis)
  • Side effects
    None
  • Adherence
    Sometimes
  • Burden
    Not at all hard to take
Dosage: 1.5 mg Daily
Advice & Tips: Pellentesque habitant morbi tristique senectus et netus et malesuada fames ac turpis egestas. Phasellus faucibus turpis sed mi maximus mattis.
Cost: < $25 monthly

Mar 10, 2015 (Started Jan 31, 2015)

  • Effectiveness
    Can't tell (for rheumatoid arthritis)
  • Side effects
    None
  • Adherence
    Usually
  • Burden
    A little hard to take
Dosage: 1.5 mg Daily
Advice & Tips: Pellentesque habitant morbi tristique senectus et netus et malesuada fames ac turpis egestas. Phasellus faucibus turpis sed mi maximus mattis.
Cost: < $25 monthly

  • 0 helpful marks

Jan 19, 2019 (Started Sep 01, 2008)

  • Effectiveness
    Major (for multiple sclerosis)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 4.5 mg Daily
Cost: $25-49 monthly

Jul 2, 2017 (Started Sep 01, 2008)

  • Effectiveness
    Major (for multiple sclerosis)
  • Side effects
    Mild (occasional insomnia, insomnia)
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 4.5 mg Daily
Cost: $50-99 monthly

Mar 5, 2017 (Started Sep 01, 2008)

  • Effectiveness
    Moderate (for multiple sclerosis)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 4.5 mg Daily
Cost: $50-99 monthly

Sep 7, 2012 (Started Sep 01, 2008)

  • Effectiveness
    Major (for multiple sclerosis)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 4.5 mg Daily
Advice & Tips: Pellentesque habitant morbi tristique senectus et netus et malesuada fames ac turpis egestas. Phasellus faucibus turpis sed mi maximus mattis.
Cost: $50-99 monthly

Feb 9, 2009 (Started Sep 01, 2008)

  • Effectiveness
    Major (for multiple sclerosis)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 4.5 mg Daily
Cost: $50-99 monthly

Sep 7, 2008 (Started Sep 01, 2008)

  • Effectiveness
    Major (for multiple sclerosis)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 4.5 mg Daily
Advice & Tips: Pellentesque habitant morbi tristique senectus et netus et malesuada fames ac turpis egestas. Phasellus faucibus turpis sed mi maximus mattis.
Cost: $50-99 monthly

  • 7 helpful marks

Oct 5, 2018 (Started Jan 17, 2013)

  • Effectiveness
    Can't tell (for increased alcohol intake)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take

Sep 12, 2013 (Started Jan 17, 2013)

  • Effectiveness
    Can't tell (for increased alcohol intake)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 4.5 mg Daily

  • 0 helpful marks
Last updated:
Showing 3 of 79 patient evaluations for Naltrexone