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What is Pyridostigmine?

Category: Prescription Drugs

Most popular types: Mestinon Mestinon Timespan Kalymin 60N

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Pyridostigmine is an acetylcholinesterase inhibitor used for the symptomatic treatment of myaesthenia gravis and as an antidote for nondepolarizing neuromuscular blockers.

See patients taking Pyridostigmine

Reported purpose & perceived effectiveness
Purpose Patients Evaluations Perceived Effectiveness
Myasthenia gravis 797 81
Fatigue 23 15
Lambert-Eaton myasthenic syndrome 19 1
Postural orthostatic tachycardia syndrome 13 7
Dysautonomia 9 10
Drooping eyelid (ptosis) 8 4

Show all 62 reasons taken

  • Major
  • Moderate
  • Slight
  • None
  • Can't tell
See all 1075 patients that have taken Pyridostigmine

Side effects

Side effects as an overall problem

Side effects as an overall problem
Severity Evaluations Percentage
Severe 7
Moderate 23
Mild 33
None 58

Commonly reported side effects and conditions associated with Pyridostigmine

Side effect Patients Percentage
Diarrhea 21
Nausea 6
Excess saliva 3
Stomach pain 3
Sweating 3
Abdominal cramps 2

Show all 47 reported side effects

Why patients stopped taking Pyridostigmine

Multiple reasons could be selected

Reason Patients Percentage
Did not seem to work 20
Doctor's advice 14
Side effects too severe 14
Other 9
Course of treatment ended 2
Expense 2
Personal research 1
See all 43 patients who've stopped taking Pyridostigmine

Duration

Stopped taking Pyridostigmine

Duration Patients Percentage
Less than 1 month 6
1 - 6 months 9
6 months - 1 year 10
1 - 2 years 5
2 - 5 years 6
5 - 10 years 3
10 years or more 2
Adherence
Adherence Evaluations Percentage
Always 82
Usually 25
Sometimes 8
Never taken as prescribed 6
Burden
Burden Evaluations Percentage
Very hard to take 7
Somewhat hard to take 8
A little hard to take 22
Not at all hard to take 84
Cost per month
Cost per month Evaluations Percentage
$200+ 1
$100-199 1
$50-99 2
$25-49 17
< $25 41
Not specified 59

What people switch to and from

Patients started taking Pyridostigmine after stopping:

Treatment Patients Percentage
Meclizine (Meclizine OTC) 1
Metoprolol (Metoprolol Tartrate) 1
Prednisone (Prednisone Intensol) 1
Senna (Senokot) 1

Patients stopped taking Pyridostigmine and switched to:

Treatment Patients Percentage
Prednisone (Prednisone Intensol) 2
Azathioprine (Imuran) 1
Droxidopa (Northera) 1
Fludrocortisone (Florinef) 1
Intravenous Immunoglobulin (IVIG) (Gammaglobulin (IVIg)) 1

Show all 7 treatments patients report switching to

Last updated:

3 patient evaluations for Pyridostigmine

Sort by: Most recent

Mar 1, 2011 (Started Aug 01, 2006)

  • Effectiveness
    None (for fatigue)
  • Side effects
    None
  • Adherence
    Sometimes
  • Burden
    Not at all hard to take
Dosage: As needed
  • 0 helpful marks

Apr 8, 2009 (Started Apr 08, 2009)

  • Effectiveness
    Moderate (for Other)
  • Effectiveness
    Moderate (for fatigue)
  • Effectiveness
    None (for double vision (diplopia))
  • Side effects
    Moderate (excess mucus)
  • Adherence
    Usually
  • Burden
    A little hard to take
Dosage: 30 mg All the time (24/7)
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Cost: $50-99 monthly
Side effects: excess mucus
  • 0 helpful marks

Aug 19, 2008 (Started Dec 17, 2005)

  • Effectiveness
    Major (for Other)
  • Effectiveness
    None (for atrophy of upper body muscles)
  • Side effects
    None
  • Adherence
    Always
  • Burden
    Not at all hard to take
Dosage: 180 mg Daily
Cost: < $25 monthly
  • 0 helpful marks
Last updated:
Showing 3 of 3 patient evaluations for Pyridostigmine