What is Sulfasalazine?
Category: Prescription Drugs
Most popular types: Salazopyrin Azulfidine Sulfazine Show all
Sulfasalazine is a 5-aminosalicylic acid derivative used primarily for ulcerative colitis and rheumatoid arthritis. It has many other uses including ankylosing spondylitis, collagenous colitis, Crohn's disease, psoriasis, psoriatic arthritis, juvenile chronic arthritis.
| Purpose | Patients | Evaluations | Perceived Effectiveness |
|---|---|---|---|
| Rheumatoid arthritis | 3591 | 167 | |
| Crohn's disease | 1223 | 22 | |
| Ulcerative colitis | 391 | 24 | |
| Psoriatic arthritis | 298 | 19 | |
| Ankylosing spondylitis | 34 | 12 | |
| Reactive arthritis | 32 | 3 |
- Major
- Moderate
- Slight
- None
- Can't tell
Side effects
Side effects as an overall problem
| Severity | Evaluations | Percentage |
|---|---|---|
| Severe | 58 | |
| Moderate | 48 | |
| Mild | 56 | |
| None | 113 |
Commonly reported side effects and conditions associated with Sulfasalazine
| Side effect | Patients | Percentage |
|---|---|---|
| Nausea | 30 | |
| Headaches | 18 | |
| Rashes (redness, swelling) | 8 | |
| Diarrhea | 7 | |
| Fatigue | 6 | |
| Stomach pain | 6 |
Why patients stopped taking Sulfasalazine
Multiple reasons could be selected
| Reason | Patients | Percentage |
|---|---|---|
| Did not seem to work | 158 | |
| Side effects too severe | 140 | |
| Doctor's advice | 95 | |
| Other | 41 | |
| Course of treatment ended | 19 | |
| Personal research | 10 | |
| Expense | 6 | |
| Change in health plan coverage | 4 |
Duration
Stopped taking Sulfasalazine
| Duration | Patients | Percentage |
|---|---|---|
| Less than 1 month | 76 | |
| 1 - 6 months | 77 | |
| 6 months - 1 year | 46 | |
| 1 - 2 years | 37 | |
| 2 - 5 years | 52 | |
| 5 - 10 years | 16 | |
| 10 years or more | 16 |
What people switch to and from
Patients started taking Sulfasalazine after stopping:
| Treatment | Patients | Percentage |
|---|---|---|
| Methotrexate (Apo-Methotrexate) | 24 | |
| Hydroxychloroquine (Plaquenil) | 13 | |
| Mesalamine (Pentasa) | 11 | |
| Adalimumab (Humira) | 9 | |
| Leflunomide (Arava) | 7 |
Patients stopped taking Sulfasalazine and switched to:
| Treatment | Patients | Percentage |
|---|---|---|
| Methotrexate (Apo-Methotrexate) | 20 | |
| Mesalamine (Pentasa) | 15 | |
| Adalimumab (Humira) | 11 | |
| Hydroxychloroquine (Plaquenil) | 8 | |
| Infliximab (Remicade) | 6 |
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