What is Doxorubicin?
Category: Prescription Drugs
Most popular types: Adriamycin Doxil
See also: ABVD regimen Bortezomib-doxorubicin-dexamethasone (PAD) Bortezomib-thalidomide-dexamethasone-cisplatin-doxorubicin-cyclophosphamide-etoposide (VTD-PACE) CALGB 9251 CODOX-M/IVAC Cytarabine-Doxorubicin Dexamethasone-thalidomide-cisplatin-doxorubicin-cyclophosphamide-etoposide (DT-PACE) Docetaxel-doxorubicin-cyclophosphamide (TAC) Doxorubicin-cyclophosphamide (AC) Doxorubicin-cyclophosphamide-docetaxel-trastuzumab Doxorubicin-cyclophosphamide-docetaxel-trastuzumab-pertuzumab Doxorubicin-cyclophosphamide-paclitaxel (ACT) Doxorubicin-cyclphophosphamide-paclitaxel-trastuzumab (AC-TH) Doxorubicin-cyclphophosphamide-paclitaxel-trastuzumab-pertuzumab (AC-THP) EPOCH FAC protocol Methotrexate-Vinblastine-Doxorubicin-Cisplatin (MVAC) Vincristine-doxorubicin-dexamethasone (VAD)
Doxorubicin is a chemotherapy agent used in the treatment of breast cancer, ovarian cancer, multiple myeloma, and AIDS-related Kaposi's sarcoma.
| Purpose | Patients | Evaluations | Perceived Effectiveness |
|---|---|---|---|
| Acute lymphocytic leukemia | 22 | 0 | |
| Osteosarcoma | 16 | 0 | |
| Breast cancer | 13 | 5 | |
| Endometrial cancer | 8 | 0 | |
| Wilms' tumor | 4 | 0 | |
| Kaposi's sarcoma | 3 | 1 |
- Major
- Moderate
- Slight
- None
- Can't tell
Side effects
Side effects as an overall problem
| Severity | Evaluations | Percentage |
|---|---|---|
| Severe | 1 | |
| Moderate | 5 | |
| Mild | 3 | |
| None | 0 |
Commonly reported side effects and conditions associated with Doxorubicin
| Side effect | Patients | Percentage |
|---|---|---|
| Fatigue | 4 | |
| Nausea | 4 | |
| Hair loss | 3 | |
| Burning sensation in soles of feet | 1 | |
| Constipation | 1 | |
| Dilated cardiomyopathy | 1 |
Why patients stopped taking Doxorubicin
Multiple reasons could be selected
| Reason | Patients | Percentage |
|---|---|---|
| Course of treatment ended | 13 | |
| Doctor's advice | 4 | |
| Side effects too severe | 3 | |
| Did not seem to work | 2 |
Duration
Stopped taking Doxorubicin
| Duration | Patients | Percentage |
|---|---|---|
| Less than 1 month | 3 | |
| 1 - 6 months | 10 | |
| 6 months - 1 year | 1 | |
| 2 - 5 years | 1 |
What people switch to and from
Patients started taking Doxorubicin after stopping:
| Treatment | Patients | Percentage |
|---|---|---|
| Vorinostat (Zolinza) | 1 |
Patients stopped taking Doxorubicin and switched to:
| Treatment | Patients | Percentage |
|---|---|---|
| Olaparib (Lynparza) | 1 |