What is Isotretinoin?
Category: Prescription Drugs
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Isotretinoin is an acne product used in the treatment of severe acne unresponsive to conventional therapy. It is being used for treatment of children with metastatic neuroblastoma or leukemia that does not respond to conventional therapy.
| Purpose | Patients | Evaluations | Perceived Effectiveness |
|---|---|---|---|
| Acne | 93 | 21 | |
| Hidradenitis suppurativa | 25 | 0 | |
| Acne breakout | 13 | 11 | |
| Granuloma annulare | 3 | 0 | |
| Subacute cutaneous lupus erythematosus | 2 | 0 | |
| Folliculitis | 1 | 1 |
- Major
- Moderate
- Slight
- None
- Can't tell
Side effects
Side effects as an overall problem
| Severity | Evaluations | Percentage |
|---|---|---|
| Severe | 5 | |
| Moderate | 13 | |
| Mild | 10 | |
| None | 1 |
Commonly reported side effects and conditions associated with Isotretinoin
| Side effect | Patients | Percentage |
|---|---|---|
| Dry skin | 11 | |
| Depressed mood | 5 | |
| Dry lips | 5 | |
| Dry eyes | 4 | |
| Dry mouth | 3 | |
| Joint pain | 3 |
Duration
Stopped taking Isotretinoin
| Duration | Patients | Percentage |
|---|---|---|
| Less than 1 month | 2 | |
| 1 - 6 months | 14 | |
| 6 months - 1 year | 10 | |
| 1 - 2 years | 2 | |
| 5 - 10 years | 2 | |
| 10 years or more | 3 |
What people switch to and from
Patients started taking Isotretinoin after stopping:
| Treatment | Patients | Percentage |
|---|---|---|
| Lymecycline | 2 | |
| Adapalene (Differin) | 1 | |
| Benzoyl Peroxide-Clindamycin Topical (Benzaclin topical) | 1 | |
| Chemotherapy | 1 | |
| Clindamycin topical (Dalacin T) | 1 |
Patients stopped taking Isotretinoin and switched to:
| Treatment | Patients | Percentage |
|---|---|---|
| Benzoyl Peroxide-Clindamycin Topical (Benzaclin topical) | 1 | |
| Sulfamethoxazole-Trimethoprim (cotrimoxazole) (Bactrim) | 1 |
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