What is Modafinil?
Category: Prescription Drugs
Most popular types: Provigil Alertec Modiodal Show all
Modafinil is stimulant used to improve wakefulness in patients narcolepsy and shift work sleep disorder or as an adjunctive therapy for obstructive sleep apnea. It may also be used for attention-deficit/hyperactivity disorder and to treat fatigue in MS and other disorders.
| Purpose | Patients | Evaluations | Perceived Effectiveness |
|---|---|---|---|
| Multiple sclerosis | 2190 | 441 | |
| Fatigue | 1664 | 741 | |
| Excessive daytime sleepiness (somnolence) | 578 | 378 | |
| Narcolepsy | 512 | 59 | |
| Idiopathic hypersomnia | 145 | 30 | |
| Brain fog | 85 | 54 |
- Major
- Moderate
- Slight
- None
- Can't tell
Side effects
Side effects as an overall problem
| Severity | Evaluations | Percentage |
|---|---|---|
| Severe | 74 | |
| Moderate | 159 | |
| Mild | 273 | |
| None | 666 |
Commonly reported side effects and conditions associated with Modafinil
| Side effect | Patients | Percentage |
|---|---|---|
| Jittery feeling | 57 | |
| Headaches | 55 | |
| Dry mouth | 51 | |
| Anxious mood | 36 | |
| Tachycardia (fast heart rate) | 30 | |
| Irritability | 21 |
Why patients stopped taking Modafinil
Multiple reasons could be selected
| Reason | Patients | Percentage |
|---|---|---|
| Did not seem to work | 316 | |
| Other | 215 | |
| Side effects too severe | 206 | |
| Expense | 185 | |
| Doctor's advice | 127 | |
| Change in health plan coverage | 97 | |
| Personal research | 36 | |
| Course of treatment ended | 19 |
Duration
Stopped taking Modafinil
| Duration | Patients | Percentage |
|---|---|---|
| Less than 1 month | 135 | |
| 1 - 6 months | 182 | |
| 6 months - 1 year | 127 | |
| 1 - 2 years | 147 | |
| 2 - 5 years | 198 | |
| 5 - 10 years | 84 | |
| 10 years or more | 30 |
What people switch to and from
Patients started taking Modafinil after stopping:
| Treatment | Patients | Percentage |
|---|---|---|
| Methylphenidate (Ritalin) | 26 | |
| Armodafinil (Nuvigil) | 22 | |
| Amphetamine-Dextroamphetamine (Adderall) | 18 | |
| Amantadine (Symmetrel) | 13 | |
| Amitriptyline (Elavil) | 2 |
Patients stopped taking Modafinil and switched to:
| Treatment | Patients | Percentage |
|---|---|---|
| Amphetamine-Dextroamphetamine (Adderall) | 46 | |
| Armodafinil (Nuvigil) | 44 | |
| Methylphenidate (Ritalin) | 14 | |
| Lisdexamfetamine (Vyvanse) | 7 | |
| Dextroamphetamine (Dexedrine) | 6 |
Last updated: