What is Phenytoin?
Category: Prescription Drugs
Most popular types: Dilantin Dilantin Kapseals Phenytoin EX Show all
Phenytoin is an antiarrhythmic and anticonvulsant agent that is used for the management of generalized tonic-clonic (grand mal), complex partial seizures; and for the prevention of seizures following head trauma/neurosurgery. It is also used for neuropathic pain.
| Purpose | Patients | Evaluations | Perceived Effectiveness |
|---|---|---|---|
| Epilepsy | 2215 | 278 | |
| Seizures (grand mal or tonic-clonic) | 75 | 48 | |
| Seizures | 53 | 58 | |
| Seizures (complex partial) | 7 | 21 | |
| Myotonia congenita | 5 | 0 |
- Major
- Moderate
- Slight
- None
- Can't tell
Side effects
Side effects as an overall problem
| Severity | Evaluations | Percentage |
|---|---|---|
| Severe | 93 | |
| Moderate | 85 | |
| Mild | 69 | |
| None | 79 |
Commonly reported side effects and conditions associated with Phenytoin
| Side effect | Patients | Percentage |
|---|---|---|
| Bleeding gums | 14 | |
| Drowsiness | 12 | |
| Dizziness | 10 | |
| Depressed mood | 9 | |
| Fatigue | 8 | |
| Memory problems | 7 |
Why patients stopped taking Phenytoin
Multiple reasons could be selected
| Reason | Patients | Percentage |
|---|---|---|
| Doctor's advice | 159 | |
| Side effects too severe | 144 | |
| Did not seem to work | 125 | |
| Other | 67 | |
| Course of treatment ended | 25 | |
| Personal research | 16 | |
| Change in health plan coverage | 5 | |
| Expense | 5 |
Duration
Stopped taking Phenytoin
| Duration | Patients | Percentage |
|---|---|---|
| Less than 1 month | 67 | |
| 1 - 6 months | 52 | |
| 6 months - 1 year | 28 | |
| 1 - 2 years | 34 | |
| 2 - 5 years | 51 | |
| 5 - 10 years | 35 | |
| 10 years or more | 78 |
What people switch to and from
Patients started taking Phenytoin after stopping:
| Treatment | Patients | Percentage |
|---|---|---|
| Lamotrigine (Lamictal) | 6 | |
| Phenobarbital (Phenobarbitalum) | 4 | |
| Carbamazepine (Tegretol) | 3 | |
| Levetiracetam (Keppra) | 3 | |
| Quinidine | 2 |
Patients stopped taking Phenytoin and switched to:
| Treatment | Patients | Percentage |
|---|---|---|
| Levetiracetam (Keppra) | 21 | |
| Carbamazepine (Tegretol) | 14 | |
| Lamotrigine (Lamictal) | 10 | |
| Divalproex sodium (Depakote) | 4 | |
| Topiramate (Topamax) | 4 |
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